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    • Reports of major impact

      Noninvasive detection of fetal trisomy 21 by sequencing of DNA in maternal blood: a study in a clinical setting

      American Journal of Obstetrics & Gynecology
      Vol. 204Issue 3p205.e1–205.e11Published online: February 11, 2011
      • Mathias Ehrich
      • Cosmin Deciu
      • Tricia Zwiefelhofer
      • John A. Tynan
      • Lesley Cagasan
      • Roger Tim
      • and others
      Cited in Scopus: 388
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        We sought to evaluate a multiplexed massively parallel shotgun sequencing assay for noninvasive trisomy 21 detection using circulating cell-free fetal DNA.
        Noninvasive detection of fetal trisomy 21 by sequencing of DNA in maternal blood: a study in a clinical setting
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