Abstract
OBJECTIVE: This study analyzed the relationship between birth weight and perinatal outcome among
women with gestational diabetes mellitus.
STUDY DESIGN: The relationship between perinatal outcome and birth weight was analyzed for 821
pregnancies of women with gestational diabetes mellitus attended in a tertiary hospital
and receiving intensive metabolic therapy (normocaloric diet, self-monitoring of blood
glucose level and individually tailored insulin regimen when needed). The Mantel-Haenszel
test was used to adjust for preterm delivery.
RESULTS: Seven percent of neonates were small for gestational age, 85% were appropriate for
gestational age, and 8% were large for gestational age. After adjustment for preterm
delivery the rates of adverse fetal outcome, low 1-minute Apgar score, and hypoglycemia
were greater among small for gestational age neonates than among appropriate and large
for gestational age infants (odds ratios 3.08, 2.51, and 3.17, respectively).
CONCLUSION: Among women with gestational diabetes mellitus who are receiving intensive therapy,
perinatal outcome is worse for small for gestational age neonates than for appropriate
and large for gestational age neonates. (Am J Obstet Gynecol 1998;179:481-5.)
Keywords
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Article info
Publication history
Accepted:
January 15,
1998
Received in revised form:
December 13,
1997
Received:
September 3,
1997
Footnotes
☆From the Endocrinology, Pediatric, and Obstetric Departments, Hospital de Sant Pau, Universitat Autònoma de Barcelona.
☆☆Reprint requests: Rosa Corcoy, PhD, Servei d’Endocrinologia, Hospital de Sant Pau, Avgda Sant Antoni Ma Claret 167, Barcelona 08025, Spain.
★0002-9378/98 $5.00 + 0 6/1/89116
Identification
Copyright
© 1998 Mosby, Inc. Published by Elsevier Inc. All rights reserved.