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Polycystic ovary syndrome: Metabolic challenges and new treatment options

  • Gloria A. Bachmann
    Affiliations
    Department of Obstetrics, Gynecology, and Reproductive Sciences and Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, and the Division of General Obstetrics and Gynecology, Robert Wood Johnson Medical School. New Brunswick, New Jersey
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      By the year 2000, approximately 50 million women will be postmenopausal. Because of increasing average life expectancy, women can anticipate spending >25 years in the postreproductive state. In light of this scenario, the global problems associated with polycystic ovary syndrome transcend the younger woman’s problems of amenorrhea, irregular menses, infertility, and hirsutism and include potential long-term metabolic and cardiovascular consequences. Long-term consequences of polycystic ovary syndrome are especially important because the problems that stem from android obesity and hyperinsulinemic conditions commence during the reproductive years and persist into the postmenopausal years.
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      References

        • Stein I
        • Leventhal M
        Amenorrhea associated with bilateral polycystic ovaries.
        Am J Obstet Gynecol. 1935; 29: 181-191