Pregnancy-induced elevation in aortic vascular smooth muscle actin in the Sprague-Dawley rat


      A component of hemodynamic responses during pregnancy may include structural changes in the arterial tree. Smooth muscle α-actin is a major structural-contractile protein of muscle cells. We observed a marked increase in expression of actin during pregnancy in the rat aorta, suggesting a structural alteration of conduit arteries. (Am J Obstet Gynecol 1997;176:212-3.)


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