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- Omega-3 fatty acid intake by age, gender, and pregnancy status in the United States: national health and nutrition examination survey 2003-2014.Nutrients. 2019; 11: 177
- Office of Disease Prevention and Health Promotion.2015–2020 dietary guidelines. health.gov. 2021; (Available at:)https://health.gov/our-work/nutrition-physical-activity/dietary-guidelines/previous-dietary-guidelines/2015Date accessed: January 20, 2020
- A review of guidance on fish consumption in pregnancy: is it fit for purpose?.Public Health Nutr. 2018; 21: 2149-2159
- Maternal fish intake during pregnancy, blood mercury levels, and child cognition at age 3 years in a US cohort.Am J Epidemiol. 2008; 167: 1171-1181
- Linking exposure to polychlorinated biphenyls with fatty fish consumption and reduced fetal growth among Danish pregnant women: a cause for concern?.Am J Epidemiol. 2008; 168: 958-965
- Dietary determinants of polyunsaturated fatty acid (PUFA) status in a high fish-eating cohort during pregnancy.Nutrients. 2018; 10: 927
- Omega-3 fatty acid addition during pregnancy.Cochrane Database Syst Rev. 2018; 11: CD003402
- Maternal plasma n-3 and n-6 polyunsaturated fatty acids during pregnancy and features of fetal health: fetal growth velocity, birth weight and duration of pregnancy.Clin Nutr. 2018; 37: 1367-1374
- Fish oil supplementation in pregnancy increases gestational age, size for gestational age, and birth weight in infants: a randomized controlled trial.J Nutr. 2019; 149: 628-634
- Association between whole-blood polyunsaturated fatty acids in pregnant women and early fetal weight.Eur J Clin Nutr. 2013; 67: 978-983
- Maternal fish consumption, fetal growth and the risks of neonatal complications: the Generation R Study.Br J Nutr. 2011; 105: 938-949
- Racial/ethnic standards for fetal growth: the NICHD Fetal Growth Studies.Am J Obstet Gynecol. 2015; 213 (e1–41): 449
- Cohort profile: NICHD Fetal Growth Studies-Singletons and Twins.Int J Epidemiol. 2018; 47 (25–25l)
- Nutrition during pregnancy: findings from the National Institute of Child Health and Human Development (NICHD) Fetal Growth Studies-Singleton cohort.Curr Dev Nutr. 2020; 5: nzaa182
- Diet during early pregnancy and development of gestational diabetes.Paediatr Perinat Epidemiol. 2008; 22: 47-59
- Ultrasound quality assurance for singletons in the National Institute of Child Health and Human Development Fetal Growth Studies.J Ultrasound Med. 2016; 35: 1725-1733
- Estimation of fetal weight with the use of head, body, and femur measurements--a prospective study.Am J Obstet Gynecol. 1985; 151: 333-337
- Fetal growth profiles of macrosomic and non-macrosomic infants of women with pregestational or gestational diabetes.Ultrasound Obstet Gynecol. 2013; 41: 390-397
- Prediction of intrauterine growth retardation via ultrasonically measured head/abdominal circumference ratios.Obstet Gynecol. 1979; 54: 597-601
- Intrauterine growth retardation. A new systematic approach based on the clinical and biochemical characteristics of this condition.J Perinat Med. 1974; 2: 147-160
- A revised birth weight reference for the United States.Obstet Gynecol. 2014; 124: 16-22
- The Slone Drug Dictionary: a research driven pharmacoepidemiology tool.Pharmacoepidemiol Drug Saf. 2003; 12: 168-169
- Diet History Questionnaire II (DHQ II) for U.S. and Canada.(Available at:)https://epi.grants.cancer.gov/dhq2/Date: 2010Date accessed: January 20, 2020
- Dietary intakes of EPA and DHA omega-3 fatty acids among US childbearing-age and pregnant women: an analysis of NHANES 2001-2014.Nutrients. 2018; 10: 416
- 2015–2020 Dietary Guidelines for Americans.8th Edition. 2015 (Available at)https://health.gov/sites/default/files/2019-09/2015-2020_Dietary_Guidelines.pdfDate accessed: January 21, 2020
- The Healthy Eating Index-2010 is a valid and reliable measure of diet quality according to the 2010 Dietary Guidelines for Americans.J Nutr. 2014; 144: 399-407
- The control of the false discovery rate in multiple testing under dependency.Ann Statist. 2001; 29: 1165-1188
- Fish intake during pregnancy, fetal growth, and gestational length in 19 European birth cohort studies.Am J Clin Nutr. 2014; 99: 506-516
- A randomized trial of prenatal n-3 fatty acid supplementation and preterm delivery.N Engl J Med. 2019; 381: 1035-1045
- Maternal fatty fish intake prior to and during pregnancy and risks of adverse birth outcomes: findings from a British cohort.Nutrients. 2019; 11: 643
- Prenatal supplementation with docosahexaenoic acid has no effect on growth through 60 months of age.J Nutr. 2015; 145: 1330-1334
- MaFOS-GDM trial: maternal fish oil supplementation in women with gestational diabetes and cord blood DNA methylation at insulin like growth factor-1 (IGF-1) gene.Clin Nutr ESPEN. 2018; 23: 73-78
- DHA supplementation and pregnancy outcomes.Am J Clin Nutr. 2013; 97: 808-815
- The effect of fish oil supplementation on maternal and neonatal outcomes: a triple-blind, randomized controlled trial.J Perinat Med. 2017; 45: 1069-1077
- Does maternal docosahexaenoic acid supplementation during pregnancy and lactation lower BMI in late infancy?.J Perinat Med. 2007; 35: 295-300
- Effects of docosahexaenoic acid supplementation during pregnancy on gestational age and size at birth: randomized, double-blind, placebo-controlled trial in Mexico.Food Nutr Bull. 2010; 31: S108-S116
- The Effect of Omega-3 docosahexaenoic acid supplementation on gestational length: randomized trial of supplementation compared to nutrition education for increasing n-3 intake from foods.BioMed Res Int. 2015; 2015123078
- Effect of docosahexaenoic acid-enriched fish oil supplementation in pregnant women with type 2 diabetes on membrane fatty acids and fetal body composition--double-blinded randomized placebo-controlled trial.Diabet Med. 2014; 31: 1331-1340
- Duration of pregnancy in relation to fish oil supplementation and habitual fish intake: a randomised clinical trial with fish oil.Eur J Clin Nutr. 2007; 61: 976-985
- The effect of prenatal docosahexaenoic acid supplementation on infant outcomes in African American women living in low-income environments: a randomized, controlled trial.Psychoneuroendocrinology. 2016; 71: 170-175
Publication stageIn Press Journal Pre-Proof
The authors report no conflict of interests.
This research was supported, in part, by the Division of Population Health, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health, and, in part, with federal funds for the NICHD Fetal Growth Studies – Singletons (contract numbers HHSN275200800013C, HHSN275200800002I, HHSN27500006, HHSN275200800003IC, HHSN275200800014C, HHSN275200800012C, HHSN275200800028C, and HHSN275201000009C). E.Y., M.L., J.L.G., and K.L.G. have contributed to this work as part of their official duties as an employee of the US Federal Government.
The institutions in the NICHD Fetal Growth Studies – Singletons include, in alphabetical order, ChristianaCare Health Systems, Newark, DE; Columbia University Medical Center, New York, NY; Fountain Valley Regional Medical Center, Fountain Valley, CA; Long Beach Memorial Medical Center, Long Beach, CA; Medical University of South Carolina, Charleston, SC; New York Hospital Queens, Flushing, NY; Northwestern University Feinburg School of Medicine, Chicago, IL; Saint Peter’s University Hospital, New Brunswisk, NJ; The Emmes Corporation, Rockville, MD (data coordinating center); Tufts University, Boston, MA; University of Alabama, Birmingham, AL; University of California, Irvine, Medical Center, Orange, CA; and Women & Infants Hospital of Rhode Island, Providence, RI.
This study has been registered on ClinicalTrials.gov (trial identifier: NCT00912132).
Cite this article as: Vafai Y, Yeung E, Roy A, et al. The association between first trimester omega-3 fatty acid supplementation and fetal growth trajectories. Am J Obstet Gynecol 2022;XX:x.ex–x.ex.