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Amniotic fluid sludge caused by intraamniotic bleeding

  • Piya Chaemsaithong
    Correspondence
    Piya Chaemsaithong, MD, PhD.
    Affiliations
    Department of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

    Perinatology Research Branch, Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, United States Department of Health and Human Services (NICHD/NIH/DHHS), Bethesda, MD and Detroit, MI
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  • Roberto Romero
    Correspondence
    Corresponding authors: Roberto Romero, MD, DMedSci.
    Affiliations
    Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI

    Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI

    Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI

    Detroit Medical Center, Detroit, MI
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  • Waranyu Lertrut
    Affiliations
    Department of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
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  • Arunee Singsaneh
    Affiliations
    Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
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  • Pisut Pongchaikul
    Affiliations
    Chakri Naruebodindra Medical Institute, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

    Integrative Computational BioScience Center, Mahidol University, Nakhon Pathom, Thailand

    Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom
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Published:August 08, 2022DOI:https://doi.org/10.1016/j.ajog.2022.08.006
      A 30-year-old gravida 4, para 1021 woman at 24+5 weeks of gestation presented to the labor and delivery unit because of the onset of vaginal bleeding and abdominal cramps 5 hours before admission. Her antenatal care was complicated by a threatened abortion and subchorionic hemorrhage diagnosed with ultrasound at 5 weeks of gestation. Her previous child was delivered vaginally at term with appropriate birthweight for gestational age. The patient’s ultrasound screening at 23 weeks of gestation revealed a normal female fetus, a sonographic short cervix (cervical length, 24.7 mm), and the presence of amniotic fluid sludge. Vaginal progesterone was administered (200 mg/d). The patient reported intermittent vaginal bleeding throughout gestation.
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