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Copper intrauterine device and incident sexually transmitted infections

Published:August 04, 2021DOI:https://doi.org/10.1016/j.ajog.2021.07.026
      Our objective was to evaluate the association between copper intrauterine devices (IUDs) and the risk for incident sexually transmitted infections (STIs). Some reports have noted a decrease in the risk for infection associated with the copper IUD, such as pelvic inflammatory disease and human papilloma virus infections,
      • Spotnitz M.E.
      • Natarajan K.
      • Ryan P.B.
      • Westhoff C.L.
      Relative risk of cervical neoplasms among copper and levonorgestrel-releasing intrauterine system users.
      ,
      • Lekovich J.P.
      • Amrane S.
      • Pangasa M.
      • et al.
      Comparison of human papillomavirus infection and cervical cytology in women using copper-containing and levonorgestrel-containing intrauterine devices.
      whereas other studies have not found any association.
      • Deese J.
      • Philip N.
      • Lind M.
      • et al.
      Sexually transmitted infections among women randomised to depot medroxyprogesterone acetate, a copper intrauterine device or a levonorgestrel implant.
      We hypothesized that the copper IUD would be associated with a reduced risk for STIs when compared with the hormonal IUDs.
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