Oxytocin challenge test for antepartum fetal assessment

Report of a clinical experience
      This paper is only available as a PDF. To read, Please Download here.
      OCT’s were performed 1,209 times on 533 fetuses at risk for UPI. OCT interpretation was negative for 72% of tests, and there were no fetal deaths within a week following a negative test. Our data thus support the concept that the use of the OCT for fetal surveillance most frequently justifies a course of nonintervention. Of 69 fetuses with a positive test, 47 were subjected to the stresses of labor with maternal hyperoxygenation and lateral positioning. Twenty of these 47 (43%) tolerated labor without biophysical evidence of distress. Reactivity of the FHR, when present during a positive test, significantly increased the likelihood that a fetus would tolerate labor. The fetal and perinatal mortality rates in the patients identified as at risk for UPI and studied with OCT’s were no greater than in a comparable group of pregnancies without identifiable risk for UPI and not studied with OCT’s.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to American Journal of Obstetrics & Gynecology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Pose S.V.
        • Escarcena L.
        • Althabe O.
        • Schwarcz R.L.
        • Ibarra-Polo A.A.
        • Quintanilla R.
        • Caldeyro-Barcia R.
        The influence of uterine contractions on the partial pressure of oxygen of the human fetus.
        in: Caldeyro-Barcia R. Méndez-Bauer C. Dawes G.S. Effects of Labour on the Foetus and Newborn. Pergamon Press, Oxford1967: 48
        • Greiss F.C.
        • Anderson S.G.
        Uterine blood flow during labor.
        Clin. Obstet. Gynecol. 1968; 11: 96
        • Myers R.E.
        • Mueller-Heubach E.
        • Adamsons K.
        Predictability of the state of fetal oxygenation from the quantitative analysis of the components of late deceleration.
        Am. J. Obstet. Gynecol. 1973; 115: 1083
        • Hammacher K.
        Früherkennung intrauteriner gefahrenzustände durch electrokardiographie und tokographie.
        in: Elert R. Hüter K.A. Prophyaxe Frühkindlicher Hirnshäden. Georg Theime Verlag, Stuttgart1966: 120
        • Hammacher K.
        • Hüter K.A.
        • Bokelmann J.
        • Werners P.H.
        Foetal heart frequency and perinatal condition of the foetus and newborn.
        Gynaecologia. 1968; 166: 349
        • Ray M.
        • Freeman R.
        • Pine S.
        • Hesselgesser R.
        Clinical experience with the oxytocin challenge test.
        Am. J. Obstet. Gynecol. 1972; 114: 1
        • Huddleston J.F.
        • Freeman R.K.
        The use of the oxytocin challenge test for the management of pregnancies at risk for uteroplacental insufficiency.
        in: Bolognese R.J. Schwarz R.H. Perinatal Medicine: Management of the High Risk Fetus and Neonate. The Williams & Wilkins Company, Baltimore1977: 68
        • Freeman R.K.
        The use of the oxytocin challenge test for antepartum clinical evaluation of uteroplacental respiratory function.
        Am. J. Obstet. Gynecol. 1975; 121: 481
        • Bishop E.H.
        Pelvic scoring for elective induction.
        Obstet. Gynecol. 1964; 24: 266
        • Freeman R.K.
        Management of acute intrapartum fetal distress.
        in: Freeman R.K. A Clinical Approach to Fetal Monitoring. Berkeley Bio-Engineering, San Leandro1974: 69
        • Paul R.H.
        • Miller F.C.
        Antepartum fetal heart rate monitoring.
        Clin. Obstet. Gynecol. 1968; 21: 375
        • Lubchenco L.O.
        • Hansman C.
        • Dressler M.
        • Boyd E.
        Intrauterine growth as estimated from live-born birth weight data at 24 to 42 weeks of gestation.
        Pediatrics. 1963; 32: 793
        • Salerno N.J.
        • Kay T.R.
        A further challenge to the validity of the weekly interval between oxytocin challenge tests.
        Am. J. Obstet. Gynecol. 1978; 130: 849
        • Bruce S.L.
        • Petrie R.H.
        • Yeh S.Y.
        The suspicious contraction stress test.
        Obstet. Gynecol. 1978; 51: 415
        • Braly P.
        • Freeman R.K.
        The significance of fetal heart rate reactivity with a positive oxytocin challenge test.
        Obstet. Gynecol. 1977; 50: 689
        • Aubry R.H.
        • Pennington J.C.
        Identification and evaluation of high-risk pregnancy: The perinatal concept.
        Clin. Obstet. Gynecol. 1973; 16: 3