Advertisement
Poster session II Clinical obstetrics, diabetes, labor, medical-surgical-disease, physiology/endocrinology, prematurity: Abstracts 237 - 386| Volume 208, ISSUE 1, SUPPLEMENT , S113, January 01, 2013

247: Pregnancy outcomes in patients diagnosed of gestational diabetes mellitus by criteria established by Carpenter and Coustan versus that by The International Association of Diabetes and Pregnancy Study Group

      Objective

      To compare the pregnancy outcomes in gestational diabetic patients by criteria established by Carpenter and Coustan (Group 1) versus that by The International Association of Diabetes and Pregnancy Study Group-IADPSG (Group 2).

      Study Design

      We performed a retrospective cohort study of pregnant patients who met criteria for GDM during the 100-g or 75-g oral glucose tolerance test (GTT). In Group 1, GDM was diagnosed using criteria established by Carpenter and Coustan with the 100-g oral GTT. Group 2 consisted of gestational diabetic patients who underwent the 75-g oral GTT and met the criteria established by IADPSG. Patients with abnormal fastng glucose were excluded.

      Results

      Group 1 and 2 consisted of 205 and 142 patients respectively who delivered in a community hospital between 2010 and 2012. There was no statistical significant difference in the percent of multiparity, body mass index, and weight gain during the pregnancy. Patients in Group 2 was diagnosed of gestational diabetes mellitus (GDM) sooner at 26.9 weeks than those in Group 1 at 27.8 weeks gestation. However, there was no statistical difference in the gestational age at delivery, neonatal birthweight, and incidence of birthweight of 4,000 gm or more. There was a statistical significant difference in the method of treatment of GDM during the pregnancy. 56.1% of patients in Group 1 while 77.9 % of patients in Group 2 required diet and exercise. Medical treatment including glyburide or insulin was required in 43.9% of Group 1 patients while only 22.1% of Group 2 patients required this mode of therapy (P = < 0.0001). There was a significant higher percent of patients in Group 1 who required cesarean delivery (49.3% vs 34%; P = 0.0108).

      Conclusion

      Using a lower threshold in the diagnosis of GDM does not seem to improve the pregnancy outcome.
      Figure thumbnail grr8