Objective
The purpose of this study was to evaluate neonatal outcome of monochorionic twin pregnancies
complicated by twin anemia-polycythemia sequence (TAPS).
Study Design
A cohort of consecutive monochorionic twins with TAPS with double survivors was included
in the study. Each twin pair with TAPS was compared with 2 monochorionic twin pairs
who were unaffected by TAPS or twin-to-twin transfusion syndrome and who were matched
for gestational age at birth. Neonatal death, severe morbidity, and cerebral injury
were studied.
Results
We included 19 twin pairs in the TAPS group and 38 control twin pairs. The incidence
of neonatal death and severe neonatal morbidity was similar in the TAPS group and
control group (3% [1/38] vs 1% [1/76] and 24% [9/38] vs 28% [21/76], respectively).
Severe cerebral injury was detected in 1 infant (5%) in the TAPS group and 1 infant
(2%) in the control group.
Conclusion
Neonatal mortality and morbidity rates in a select population of TAPS neonates are
similar to control neonatal rates.
Key words
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Article info
Publication history
Published online: April 26, 2010
Accepted:
February 10,
2010
Received in revised form:
October 29,
2009
Received:
September 25,
2009
Footnotes
Authorship and contribution to the article is limited to the 6 authors indicated. There was no outside funding or technical assistance with the production of this article.
Cite this article as: Lopriore E, Slaghekke F, Oepkes D, et al. Clinical outcome in neonates with twin anemia-polycythemia sequence. Am J Obstet Gynecol 2010;203:54.e1-5.
Reprints not available from the authors.
Identification
Copyright
© 2010 Mosby, Inc. Published by Elsevier Inc. All rights reserved.
