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294: Regional and monthly variation in rates of preeclampsia at delivery among US births

      Objective

      To determine if there is a correlation between calendar month and rates of preeclampsia at delivery among US births divided by geographic region.

      Study Design

      We queried the National Center for Health Statistics birth data from 2000-2005. We collected data on total deliveries and deliveries complicated by pregnancy induced hypertension. Data were stratified by month and by the four regions of the US as defined by the US Census, excluding AK and HI.

      Results

      There were 24,446,824, deliveries in the US from 2000-2005 with 928,854 cases of preeclampsia (incidence=3.8%). Rates of preeclampsia in all four geographic regions showed a similar monthly variation. The Midwest and South had higher rates of preeclampsia at delivery during all months of the year (p<0.001).
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      Conclusion

      All four geographic regions of the continental US show similar monthly variation in rates of preeclampsia at delivery, and the Midwest and South have higher overall rates of preeclampsia at delivery when compared with the West and East.