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October 2008Volume 199, Issue 4, Pages 385.e1–385.e5
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Perinatal outcomes among Asian–white interracial couples

Presented at the 28th annual meeting of the Society for Maternal–Fetal Medicine, Dallas, TX, Jan. 28-Feb. 2, 2008.

Michael J. Nystrom
x
Michael J. Nystrom
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Affiliations

  • Department of Obstetrics and Gynecology, Stanford University Medical Center, Stanford, CA
, MD
,
Aaron B. Caughey
x
Aaron B. Caughey
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Affiliations

  • Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, School of Medicine, San Francisco, CA
, MD, MPP, MPH, PhD
,
Deirdre J. Lyell
x
Deirdre J. Lyell
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Affiliations

  • Department of Obstetrics and Gynecology, Stanford University Medical Center, Stanford, CA
, MD
,
Maurice L. Druzin
x
Maurice L. Druzin
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Affiliations

  • Department of Obstetrics and Gynecology, Stanford University Medical Center, Stanford, CA
, MD
,
Yasser Y. El-Sayed
x
Yasser Y. El-Sayed
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Affiliations

  • Department of Obstetrics and Gynecology, Stanford University Medical Center, Stanford, CA
, MD
Perinatal outcomes among Asian–white interracial couples
DOI: https://doi.org/10.1016/j.ajog.2008.06.065

Objective

To investigate whether perinatal outcomes among interracial Asian-white couples are different than among Asian-Asian and white-white couples.

Study Design

This was a retrospective study of Asian, white, and Asian-white couples delivered at the Lucile Packard Children's Hospital from 2000-2005. Asian-white couples were subdivided into white-mother/Asian-father or Asian-mother/white-father. Perinatal outcomes included gestational diabetes, hypertensive disorders of pregnancy, preterm delivery, birth weight >4000 g and <2500 g, and cesarean delivery.

Results

In the study population of 868 Asian-white, 3226 Asian, and 5575 white couples there were significant outcome differences. Compared with white couples, Asian-white couples had an increased incidence of gestational diabetes (aOR 2.4 for white-mother/Asian-father and aOR 2.6 for Asian-mother/white-father), though not as high as Asian couples (aOR 4.7). Asian-white couples had larger babies (median 3360 g for Asian-mother/white-father and 3320 g for white-mother/Asian-father vs 3210 g for Asian, P < .001), but only Asian-mother/white-father couples had an increased rate of cesarean delivery (aOR 1.3-2.0).

Conclusion

Significant differences in perinatal outcomes exist between Asian, white, and interracial Asian-white couples.

Key words:

Asian, white, interracial Asian-white, perinatal outcomes

Cite this article as: Nystrom MJ, Caughey AB, Lyell DJ, et al. Perinatal outcomes among Asian–white interracial couples. Am J Obstet Gynecol 2008;199:385.e1-385.e5.

Reprints not available from the authors.

© 2008 Mosby, Inc. Published by Elsevier Inc. All rights reserved.
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October 2008Volume 199, Issue 4, Pages 385.e1–385.e5