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Society for maternal-fetal medicine

New Orleans, LA—February 2–7, 2004
        Thursday, February 5, 2004
        8:00am to 10:00amOral Plenary Session 1Grand Ball Room A-B
        Moderators: Jay D. Iams, MD, President
        Haywood L. Brown, MD, Immediate
        Past President Nancy S. Green, MD,
        Medical Director, March of Dimes and 2004
        Honorary Member
        8:001
        The Dru Carlson Memorial Award for Best Research in Ultrasound and Genetics
        FIRST- AND SECOND-TRIMESTER EVALUATION OF RISK (FASTER) TRIAL: PRINCIPAL RESULTS OF THE NICHD MULTICENTER DOWN SYNDROME SCREENING STUDYFergal D. Malone,1 Nicholas J. Wald,2 Jacob A. Canick,3 Robert H. Ball,4 David A. Nyberg,5 Christine H. Comstock,6 Radek Bukowski,7 Richard L. Berkowitz,8 Susan J. Gross,9 Lorraine Dugoff,10 Sabrina D. Craigo,11 Ilan E. Timor,12 Stephen R. Carr,3 Honor M. Wolfe,13 Kimberly A. Dukes,14 Diana W. Bianchi,11 Alicja Rudnicka,2 Allan Hackshaw,2 Geralyn Lambert-Messerlian,3 Mary E. D'Alton,11Columbia University, New York, New York 2Wolfson Institute of Preventive Medicine, London 3Brown University, Providence, RI 4University of Utah, Salt Lake City, UT 5Swedish Medical Center, Seattle, WA 6William Beaumont Medical Center, Royal Oak, MI 7University of Texas Medical Branch, Galveston, TX 8Mount Sinai Medical Center, New York, New York 9Albert Einstein College of Medicine, New York, New York 10University of Colorado Health Sciences Center, Denver, CO 11Tufts University, Boston, MA 12New York University, New York, New York 13UNC Medical Center, Chapel Hill, NC 14DM-STAT, Boston, MA
        8:152A RANDOMIZED TRIAL OF SINGLE VS WEEKLY COURSES OF CORTICOSTEROIDSRonald J. Wapner,11for the NICHD MFMU Network, Rockville, MD
        8:303IMMUNOMODULATORS PLUS ANTIBIOTICS TO PREVENT PRETERM DELIVERY IN EXPERIMENTAL INTRA-AMNIOTIC INFECTION (IAI)M. Gravett,1 D Sadowsky,1 S Witkin,2 M Novy,11Or Hlth Sci U, Portland, OR 2Weill Med Col, New York, NY
        8:454FETOSCOPIC LASER SURGERY VERSUS SERIAL AMNIODRAINAGE IN THE MANAGEMENT OF SEVERE TWIN-TO-TWIN TRANSFUSION SYNDROME AT MID-GESTATION: A RANDOMIZED CONTROLLED TRIALMarie-Victoire Senat,1 Jan Deprest,2 Michel Boulvain,3Yves Ville,11Université Paris Ouest, Obstetrics/Gynecology, Poissy 2Leuven University, Obstetrics/Gynecology, Leuven 3University of Geneva, Obstetrics/Gynecology, Geneva
        9:005
        The March of Dimes Award for Best Research in Prematurity
        INTERCONCEPTIONAL ANTIBIOTICS TO PREVENT SPONTANEOUS PRETERM BIRTH (SPTB): A RANDOMIZED TRIALWilliam Andrews,1 Robert Goldenberg,1 John Hauth,1 Suzanne Cliver,11University of Alabama at Birmingham, Obstetrics/Gynecology, Birmingham, AL
        9:156ACUTE RISE IN CIRCULATING SFLT-1 MAY HERALD PREECLAMPSIARichard Levine,1 Sharon Maynard,2 Cong Qian,3 Kee-Hak Lim,2 Lucinda England,1 Kai Yu,1 Enrique Schisterman,1 Ravi Thadhani,4 Benjamin Sachs,2 Franklin Epstein,2 Baha Sibai,5 Vikas Sukhatme,2 Ananth Karumanchi,21NICHD / DHHS, Epidemiology & Biometry, Bethesda, MD 2Beth Israel Deaconess Medical Center, Medicine, Obstetrics & Gynecology, Boston, MA 3Allied Technology Group, Rockville, MD 4Massachusetts General Hospital, Medicine, Boston, MA 5University of Cincinnati, Obstetrics & Gynecology, Cincinnati, OH
        9:307OUTCOMES OF CHILDREN AT 2 YEARS OF AGE IN THE TERM BREECH TRIALHilary Whyte,1 Mary Hannah,2 Saroj Saigal,3 Term Breech Trial Collaborative Group,41Hospital for Sick Children, Paediatrics, Toronto, Ontario 2University of Toronto, Obstetrics and Gynaecology, Toronto, Ontario 3McMaster University, Paediatrics, Hamilton, Ontario 4University of Toronto, MIRU, Toronto, Ontario
        9:458THE MFMU CESAREAN REGISTRY: TRIAL OF LABOR AFTER PRIOR CESAREAN DELIVERY: MATERNAL AND PERINATAL OUTCOMEMark B. Landon,11for the NICHD MFMU Network, Bethesda, MD
        Thursday, February 5, 2004
        1:15pm to 3:30pmOral Concurrent Session 1Grand Ball Room A
        Diabetes/Hypertension/Medical-Surgical Complications
        Moderators: Nancy C. Chescheir, MD
        Michael R. Foley, MD
        1:159HYPERGLYCEMIA DOWNREGULATES THE PKC-CPLA2 SIGNAL CASCADE IN EMBRYOS AND YOLK SACS OF DIABETIC RATSE. Reece,1 S. James,1 Yingking Wu,1 Patrycja Krakowiak,1 Mario Cleves,1 Stepan Melnyk,11University of Arkansas for Medical Sciences College of Medicine, Little Rock, AR
        1:3010PLASMA ADIPONECTIN CONCENTRATIONS IN EARLY PREGNANCY AND SUBSEQUENT RISK OF GESTATIONAL DIABETES MELLITUSMichelle Williams,1Chunfang Qiu,1 Martin Muy-Rivera,1 Surab Vadachkoria,1 Tara Song,1 David Luthy,21Swedish Medical Center, Center for Perinatal Studies, Seattle, WA 2Swedish Medical Center, Obstetrics & Gynecology, Seattle, WA
        1:4511ABNORMAL HOMOCYSTEINE METABOLISM AND GLUTATHIONE DEPLETION IN YOLK SACS AND EMBRYOS OF DIABETIC RATSS. James,1 YingKing Wu,1 Stepan Melnyk,1 Patrycja Krakowiak,1 Mario Cleves,1 E. Reece,11University of Arkansas for Medical Sciences College of Medicine, Little Rock, AR
        2:0012FETAL ORIGIN OF DISEASE: THE CONTRIBUTION OF GENDER TO THE EFFECT OF UTERINE ENVIRONMENT AND GENETIC IMPRINTING ON VASCULAR REACTIVIY IN OFFSPRING OF TRANSGENIC MICEJosje Langenveld,1 Monica Longo,2 Yuri Vedernikov,2 Garland Anderson,2 Dirk Kieback,1 Robert Garfield,2 George Saade,21Maastricht University Medical Center, Dept. of Obstetrics & Gynecology, Maastricht 2University of Texas Medical Branch, Dept. of Obstetrics & Gynecology, Galveston, TX
        2:1513RISK OF BIRTH DEFECTS ASSOCIATED WITH ANTIRETROVIRAL EXPOSURE DURING PREGNANCYKaren Beckerman,1 Deborah Covington,2 Heather Watts,3 Hugh Tilson,4 Scott Chavers,5 Susan Sacks,61New York University School of Medicine, Department of Ob-Gyn, New York, NY 2PharmaResearch Corp, A member of the Inveresk Group, Wilmington, NC 3National Institute of Child Health and Human Development, Pediatric, Adolescent, Maternal AIDS Branch, Rockville, MD 4University of North Carolina at Chapel Hill, School of Public Health, Chapel Hill, NC 5GlaxoSmithKline, Epidemiology, Research Triangle Park, NC 6F. Hoffmann-La Roche, Ltd, Epidemiology, Nutley, NJ
        2:3014FIRST-TRIMESTER PLACENTAL GROWTH FACTOR, SFLT-1, AND RISK FOR PREECLAMPSIAJeffrey Eckerr,1 Ananth Karumanchi,2 James Roberts,3 Robert Taylor,4 Richard Levine,5 Ravi Thadhani,61Harvard University, Obstetrics, Gynecology & Reproductive Biology, Boston, MA 2Beth Israel Deaconess Medical Center, Medicine, Boston, MA 3University of Pittsburgh, Obstetrics, Gynecology and Reproductive Sciences, Pittsburgh, PA 4University of California, San Francisco, Obstetrics, Gynecology and Repro. Sciences, San Francisco, CA 5National Institutes of Health, Epidemiology, Bethesda, MD 6Massacusetts General Hospital, Boston, MA
        2:4515A RANDOMIZED TRIAL OF TEMPORIZING MANAGEMENT WITH OR WITHOUT PLASMA VOLUME EXPANSION IN SEVERE AND EARLY PREECLAMPSIA: MATERNAL MORBIDITYAnnelies Rep,1 Wessel Ganzevoort,2 Hans Wolf,2 Hanneke De Vries,11VU University Medical Center, Amsterdam 2Academisch Medisch Centrum, Amsterdam
        3:0016TRANSCRIPTION LEVELS OF VEGFR-1 IN PRETERM PREECLAMPSIARamen Chmait,1 Andrew Hull,1 Thomas Moore,1 Lubi Bogic,21University of California, San Diego, Reproductive Medicine, San Diego, CA 2University of California, San Diego, Reproductive Medicine, La Jolla, CA
        3:1517PERITONEAL CLOSURE AT PRIMARY CESAREAN SECTION DECREASES ADHESION FORMATIONDierdre Lyell,1 Aaron Caughey,2 Emily Hu,1 Kay Daniels,11Stanford University, Obstetrics & Gynecology, Stanford, CA 2University of California, San Francisco, Obstetrics & Gynecology, San Francisco, CA
        Thursday, February 5, 2004
        1:15pm to 3:30pmOral Concurrent Session 2Grand Ball Room B
        Antepartum Fetal Assessment/Fetus/Prematurity
        Moderators: Robert J. Sokol, MD
        Jonathan W. Weeks, MD
        1:1518
        Dr. Rodney Edwards is the SMFM 2001–2003 Scholarship Award recipient.
        DO CERVICAL FLUID CONCENTRATIONS OF ANTIBODIES MODULATE THE RISK OF PRETERM DELIVERY ASSOCIATED WITH CERVICAL LENGTH?Rodney Edwards,1 Ronald Ferguson,1 Susan Gentry,1 Jonathan Shuster,2 Patrick Duff,11University of Florida, Obstetrics and Gynecology, Gainesville, FL 2University of Florida, Statistics, Gainesville, FL
        1:3019PERINATAL EFFECT OF MAGNESIUM SULFATE ADMINISTERED FOR TOCOLYSISJohn Elliott,1 Thomas Garite,1 Reese Clark,1 Andrew Combs,11Obstetrix Medical Group, Sunrise, FL
        1:4520PROTEOMIC PROFILING OF PREMATURE LABOR: A METHOD TO IDENTIFY CLINICAL BIOMARKERS AND MECHANISMS OF DISEASERoberto Romero,1 Tinnakorn Chaiworapongsa,1 Ricardo Gomez,1 Yeon Mee Kim,1 Samuel Edwin,1Emmanuel Bujold,2 Bo Yoon,31Perinatology Research Branch, NICHD/NIH/DHHS, Detroit, MI 2Wayne State University, Obstetrics and Gynecology, Detroit, MI 3Seoul National University, Seoul
        2:0021POSTNATAL THERAPY TO PREVENT ALCOHOL-INDUCED LEARNING ABNORMALITIES IN FETAL ALCOHOL SYNDROMECatherine Spong,1 Lorraine Wood,1 Sarah Poggi,2 Daniel Abebe,11SDMP, LDN, NICHD, NIH, Bethesda, MD 2Georgetown University, Obstetrics and Gynecology, Washington, DC
        2:1522LOCALIZED INTRAUTERINE INFLAMMATION ELICITS A BRAIN-SPECIFIC TH1/TH2 RESPONSE AND RESULTS IN NEURONAL DAMAGEMichal Elovitz,1 Zhao Wang,11University of Pennsylvania, Obstetrics and Gynecology, Philadelphia, PA
        2:3023FETAL BRAIN GROWTH AND HEAD BIOMETRY FOLLOWING IN UTERO REPAIR OF MYELOMENINGOCELE (MMC)Enrico Danzer,1 Mark P Johnson,1 R. Douglas Wilson,1 Holly Hedrick,1 Timothy Crombleholme,1 Alan Flake,1 Uwe Schwarz,1 Mayadah Shabbout,1 Leslie Sutton,2 N Scott Adzick,11Children's Hospital of Philadelphia, Center for Fetal Diagnosis & Treatment, Philadelphia, PA 2Children's Hospital of Philadelphia, Pediatric Neurosurgery, Philadelphia, PA
        2:4524IN VITRO CHARACTERIZATION OF CORTICOSTEROID REDOSING (THE “RESCUE APPROACH”)Alex Vidaeff,1 Joseph Alcorn,2 Susan Ramin,1 Larry Gilstrap,11University of Texas Health Science Center at Houston, Obstetrics, Gynecology and Reproductive Sciences, Houston, TX 2University of Texas Health Science Center at Houston, Pediatrics, Houston, TX
        3:0025INCREASED VULNERABILITY OF LIVER AND PANCREAS ORGAN GROWTH IN OFFSPRING OF UNDERNOURISHED RAT DAMSMina Desai,1 Jooby Babu,1 Dave Gayle,1 Linda Day,1 Marie Beall,1 Michael Ross,11Harbor-UCLA Medical Center, Department of Obstetrics and Gynecology, Torrance, CA
        3:1526RISK FACTORS FOR NEONATAL ORGAN DAMAGE AMONG NEWBORNS AT GESTATIONAL AGE >34 WEEKS AND UMBILICAL ARTERIAL pH <7.00Suneet Chauhan,1 Nancy Hendrix,1 Everett Magann,1 James Bofill,2 John Morrison,21Spartanburg Regional Medical Center, Spartanburg, SC 2University of Mississippi Medical Center, Obstetrics and Gynecology, Jackson, MS
        Friday, February 6, 2004
        8:00am to 10:00amOral Plenary Session II (Fellows Plenary)Grand Ball Room A-B
        Moderators: Larry C. Gilstrap, MD
        Sarah J. Kilpatrick, MD, PhD
        8:0027EXPRESSION OF HYPOXIA-RELATED TRANSCRIPTS DEFINES HISTOLOGICAL CHANGES IN THE TERM HUMAN PLACENTASolange Wyatt,1 Frederick Kraus,1 Cheong-Rae Roh,1 D. Michael Nelson,1 Yoel Sadovsky,11Washington University, Obstetrics & Gynecology and Cell Biology & Physiology, St. Louis, MO
        8:1528MATERNAL INFECTION-INDUCED WHITE MATTER INJURY IS REDUCED BY TREATMENT WITH INTERLEUKIN-10Sheryl Rodts-Palenik,1 Yi Pang,2 Brad Thigpen,1 Zhengwei Cai,2 Philip Rhodes,2 James Martin Jr.,1 Joey Granger,3 William Bennett,11University of Mississippi Medical Center, Obstetrics & Gynecology, Jackson, MS 2University of Mississippi Medical Center, Pediatrics, Jackson, MS 3University of Mississippi Medical Center, Physiology & Biophysics, Jackson, MS
        8:3029POLYMORPHISMS IN THE TUMOR NECROSIS FACTOR ALPHA AND HEAT SHOCK PROTEIN HSP70-2 GENES AND PRETERM PREMATURE RUPTURE OF THE MEMBRANES IN MULTIFETAL GESTATIONSRobin B. Kalish,1 Santosh Vardhana,1 Sriram C. Perni,1 Meruka Gupta,1 Steven S. Witkin,11Weill Medical College of Cornell University, Obstetrics and Gynecology, New York, NY
        8:4530THE EFFECT OF A MATRIX METALLOPROTEINASE-1 (MMP1) INHIBITOR ON INFLAMMATION-MEDIATED PRETERM DELIVERYKaren Koscica,1 Cande Ananth,1 Sandra Reznik,21UMDNJ-Robert Wood Johnson Medical School/Robert Wood Johnson University Hospital, Obstetrics, Gynecology and Reproductive Sciences, New Brunswick, NJ 2Albert Einstein College of Medicine, Pathology, Bronx, NY
        9:0031NITRIC OXIDE/CYCLIC GUANOSINE 3,5 MONOPHOSPHATE RESPONSE TO CYCLOOXYGENASE (COX)-2 INHIBITION IN A RABBIT MODEL OF RU486-INDUCED PRETERM BIRTHDavid Gorenberg,1 Kay Beharry,2 Aamir Akmal,3 Kenji Nishihara,3 Joshua Waltzman,3 Tamerou Asrat,31University of California, Irvine, Obstetrics and Gynecology, Orange, CA 2University of California, Irvine, Pediatrics, Orange, CA 3Long Beach Memorial Medical Center, Obstetrics and Gynecology, Long Beach, CA
        9:1532POLYMORPHISM IN INTRON 2 OF INTERLEUKIN 1 RECEPTOR ANTAGONIST GENE, ABNORMAL VAGINAL MICROFLORA IN MIDTRIMESTER, AND PRETERM DELIVERYMehmet R. Genc,1 Andrew Onderdonk,2 Santosh Vardhana,3 Mary L. Delaney,2 Errol R. Norwitz,1 Ruth E. Tuomala,4 Lilly-Rose Paraskevas,3 Steven S. Witkin,31Brigham and Women's Hospital, Obstetrics & Gynecology, Boston, MA 2Harvard University, Laboratory Medicine and Pathology, Boston, MA 3Cornell University Medical College, Div. Immunology and Infectious Diseases ; Obstetrics & Gynecology, New York, NY 4Harvard University, Obstetrics and Gynecology, Boston, MA
        9:3033IMPACT OF MATERNAL FETAL SURGERY FOR MYELOMENINGOCELE ON THE PROGRESSION OF VENTRICULOMEGALY IN UTEROAmy Adelberg,1 Angela Blotzer,2 Gary Koch,2 Rachael Moise,1 Nancy Chescheir,1 Honor Wolfe,31University of North Carolina at Chapel Hill, Obstetrics/Gynecology, Chapel Hill, NC 2University of North Carolina, School of Public Health, Chapel Hill, NC 3University of North Carolina, Obstetrics/Gynecology, Chapel Hill, NC
        9:4534INCREASED LARGE-VESSEL CEREBRAL BLOOD FLOW IN SEVERE PREECLAMPSIA BY MR EVALUATIONGerda Zeeman,1 Mustapha Hatab,2 Diane Twickler,21University of Texas Southwestern Medical School, Obstetrics and Gynecology, Dallas, TX 2University of Texas Southwestern Medical School, Radiology, Dallas, TX
        Friday, February 6, 2004
        1:15pm to 3:30pmOral Concurrent Session 3 (Fellow Plenary)Grand Ball Room A
        Intrapartum Fetal Assessment/Labor/Operative Ob/Clinical Ob
        Moderators: James N. Martin, Jr, MD
        Alan Peaceman, MD
        1:1535NON-INVASIVE MAGNETOMYOGRAPHIC RECORDINGS OF THE UTERUS TO PREDICT LABOR IN TERM PREGNANCIESCurtis Lowery,1 Hubert Preissl,1 James Wilson,2 Coskun Bayrak,3 Jonathan Norton,4 Helen Kay,1 Pam Murphy,1 Hyrettin Kolukisaog,3 Hari Eswaran,11University of Arkansas for Medical Sciences, Ob/Gyn, Little Rock, AR 2University of Arkansas at Little Rock, GIT, Little Rock, AR 3University of Arkansas at Little Rock, Computer Science, Little Rock, AR 4University of Arkansas for Medical Sciences, Biostatistics, Little Rock, AR
        1:3036CROSS-LINKED COLLAGEN IN THE CERVIX OF PREGNANT WOMEN WITH CERVICAL INSUFFICIENCYDietmar Schlembach,1 Holger Maul,2 Cordula Fittkow,3 Gayle Olson,1 George Saade,1 Robert Garfield,11University of Texas Medical Branch, Department of Obstetrics & Gynecology, Galveston, TX 2University of Hannover, Department of Obstetrics & Gynecology, Hannover 3University of Freiburg, Department of Obstetrics & Gynecology, Freiburg
        1:4537PROSPECTIVE RANDOMIZED CLINICAL TRIAL OF CERVICAL RIPENING WITH MISOPROSTOL FOR EITHER 8 OR 24 HOURSAllahyar Jazayeri,1 M. Jazayeri,1 A. Jamal,2 L. Eslamian,2 V. Marsoosi,2 S. Borna,21Bellin Health Center, Maternal Fetal Medicine, Green Bay, WI 2Tehran Uiversity Medical School, Maternal Fetal Medicine, Tehran
        2:0038THE EFFICACY OF ORAL VERSUS VAGINAL MISOPROSTOL FOR SECOND-TRIMESTER TERMINATION OF PREGNANCY: A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED TRIALGenevieve Roy,1 Ema Ferreira,2 Lynda Hudon,3 Gerald Marquette,41University of California, San Francisco, Obstetrics, Gynecology and Reproductive Sciences, San francisco, CA 2Université de Montreal, Faculté de pharmacie, Montreal, Quebec 3Université de Montreal, Department of Obstetrics and Gynecology, Montreal, Quebec 4University of British Columbia, Department of Obstetrics and Gynecology, Vancouver, British Columbia
        2:1539INFLUENCE OF THE POLYMORPHIC FETAL INTERLEUKIN-1 RECEPTOR ANTAGONIST (IL-1RA) GENOTYPE ON PREGNANCY HISTORYSriram C. Perni,1 Santosh Vardhana,1 Sara L. Tuttle,1 Robin B. Kalish,1 Stephen T. Chasen,1 Steven S. Witkin,11Weill Medical College of Cornell University, Obstetrics & Gynecology, New York, NY
        2:3040AN ALLERGIC REACTION CAN INDUCE PREMATURE LABOR AND DELIVERY, WHICH CAN BE PREVENTED BY TREATMENT WITH ANTIHISTAMINICS AND CROMOLYN SODIUMEgle Bytautiene,1 Roberto Romero,2 Yuri Vedernikov,1 George Saade,1 Robert Garfield,11University of Texas Medical Branch, Department of Obstetrics and Gynecology, Galveston, TX 2Wayne State University, Department of Obstetrics and Gynecology, Detroit, MI
        2:4541THE MFMU CESAREAN REGISTRY: COMPLICATIONS OF ANESTHESIA FOR CESAREAN DELIVERYSteven L. Bloom,11for the NICHD MFMU Network, Bethesda, MD
        3:0042PROSPECTIVE RANDOMIZED COMPARISON OF INTRA-ANAL ELECTROMYOGRAPHIC BIOFEEDBACK AND INTRA-ANAL ELECTROMYOGRAPHIC BIOFEEDBACK AUGMENTED WITH ELECTRICAL STIMULATION OF THE ANAL SPHINCTERRhona Mahony,1 Patricia Malone,2 Judith Nalty,2 Mary Cassidy,3 P. Ronan O'Connell,3 Colm O'Herlihy,11University College Dublin, Obstetrics and Gynaecology, Dublin 2 2University College Dublin, Physiotherapy, Dublin 2 3University College Dublin, Surgery, Dublin 2
        3:1543LONG-TERM EFFECTS OF CHILDBIRTH ON FECAL CONTINENCE AND PUDENDAL NERVE FUNCTIONMaeve Eogan,1 Conor O'Brien,1 Michael Behan,2 P. Ronan O'Connell,3 Colm O'Herlihy,41University College Dublin, Obstetrics & Gynaecology, Dublin 2 2University College Dublin, Radiology, Dublin 7 3University College Dublin, Surgery, Dublin 7 4University College Dublin, Obstetrics and Gynaecology, Dublin 2
        Friday, February 6, 2004
        1:15pm to 3:30pmOral Concurrent Session 4Grand Ball Room B
        Fetus/Physiology-Endocrinology
        Moderators: T. Murphy Goodwin, MD
        E. Albert Reece, MD, PhD
        1:1544GLYCEMIC PROFILE IN PREGNANCY: WHAT IS NORMAL?Yariv Yogev,1 Oded Langer,1 Rony Chen,2 Avi Ben Haroush,2 Moshe Hod,21St. Luke's Roosevelt Hospital Center, Department of Obstetrics and Gynecology, New York, NY 2Rabin Medical Center, Perinatal Division, Department of Obstetrics and Gynecology, Petach-Tikva
        1:3045LATE TRACHEAL OCCLUSION REVERSES PERIPHERIC MUSCULARIZATION OF PULMONARY VESSELS IN A RABBIT MODEL OF DIAPHRAGMATIC HERNIAXenia Roubliova,1 Jun Wu,1 Jaques Jani,1 Pascal Vaast,1 Erik Verbeken,2 Jan Deprest,11Centre Surgical Technologies, Faculty of Medicine, Leuven 2Pathology Institute, Faculty of Medicine, Leuven
        1:4546CEREBRAL PALSY IS STRONGLY ASSOCIATED WITH SEVERE INTRAUTERINE GROWTH RESTRICTION IN TERM BUT NOT IN PRETERM CASESBo Jacobsson,1 Andre Francis,2 Gudrun Hagberg,3 Henrik Hagberg,1 Jason Gardosi,21Perinatal Center, Göteborg, 2West Midlands Perinatal Institute, Birmingham, 3Dept. of Pediatrics, Göteborg
        2:0047SKIN: AN ACTIVE COMPONENT OF THE FETAL INNATE IMMUNE SYSTEMYeon Mee Kim,1 Gi Jin Kim,1 Mi Ran Kim,1 Tinnakorn Chaiworapongsa,1 Jimmy Espinoza,1 Bo Yoon,2 Emmanuel Bujold,3 Roberto Romero,11Perinatology Research Branch, NICHD/NIH/DHHS, Detroit, MI 2Seoul National University, Seoul 3Wayne State University, Obstetrics and Gynecology, Detroit, MI
        2:1548THYROID-STIMULATING HORMONE (TSH) VALUES IN TWIN VERSUS SINGLETON PREGNANCIESJodi Dashe,1 Brian Casey,1 Donald McIntire,1 C. Edward Wells,1 William Byrd,1 Kenneth Leveno,1 F. Gary Cunningham,11University of Texas Southwestern Medical Center, Obstetrics and Gynecology, Dallas, TX
        2:3049IN UTERO TRANSPLANTATION OF AUTOLOGOUS AND ALLOGENEIC FETAL LIVER STEM CELLS IN FETAL SHEEPDaniel Surbek,1 Andreina Schoeberlein,1 Lisbeth Dudler,1 Wolfgang Holzgreve,11University of Basel, Obstetrics and Gynecology, Basel
        2:4550FETAL THROMBOPHILIC POLYMORPHISMS ARE NOT A RISK FACTOR FOR CEREBRAL PALSYCatherine Gibson,1 Alastair MacLennan,1 Bill Hague,2 Zbigniew Rudzki,3 Phillipa Sharpe,4 Annabelle Chan,5 Gustaaf Dekker,11Adelaide University, Obstetrics and Gynaecology, Adelaide, South Australia 2Women's and Children's Hospital, Adelaide, Obstetrics and Gynaecology, North Adelaide, South Australia 3Institute of Medical and Veterinary Sciences, Molecular Pathology, Adelaide, South Australia 4Women's and Children's Hospital, South Australian Clinical Genetics Service, Adelaide, South Australia 5Department of Human Services, Pregnancy Outcomes Unit, Adelaide, South Australia
        3:0051NEONATAL WHITE MATTER INJURY IS ASSOCIATED WITH CULTURE-POSITIVE INFECTIONS AND ONLY RARELY WITH METABOLIC ACIDOSISKarishma Rai,1 Cynthia Holcroft,2 Marilee Allen,3 Ernest Graham,21Ross Medical School, Dominica, 2Johns Hopkins University School of Medicine, Gyn-Ob, Baltimore, MD 3Johns Hopkins University School of Medicine, Pediatrics, Baltimore, MD
        Friday, February 6, 2004
        1:15pm to 3:30pmOral Concurrent Session 4Grand Ball Room B
        Fetus/Physiology-Endocrinology
        Moderators: T. Murphy Goodwin, MD
        E. Albert Reece, MD, PhD
        3:1552FIRST-TRIMESTER ORIGINS OF FETAL GROWTH IMPAIRMENT AND ITS CONSEQUENCES: RESULTS FROM THE FASTER TRIALRadek Bukowski,1 George Saade,1 Fergal D. Malone,2 T. Flint Porter,3 David A. Nyberg,4 Christine H. Comstock,5 Gary D. V. Hankins,1 Richard L. Berkowitz,6 Paula Reingold,7 Lorraine Dugoff,8 Sabrina D. Craigo,9 Ilan E. Timor,10 Stephen R. Carr,11 Honor M. Wolfe,12 Nicole Tibbetts,13 Mary E. D'Alton,21University of Texas Medical Branch, Department of Obstetrics and Gynecology, Galveston, TX 2Columbia University, Department of Obstetrics and Gynecology, New York, NY 3University of Utah, Department of Obstetrics and Gynecology, Salt Lake City, UT 4Swedish Medical Center, Department of Obstetrics and Gynecology, Seattle, WA 5William Beaumont Medical Center, Department of Obstetrics and Gynecology, Royal Oak, MI 6Mount Sinai Medical Center, Department of Obstetrics and Gynecology, New York, NY 7Montefiore Medical Center, Department of Obstetrics and Gynecology, Bronx, NY 8University of Colorado, Department of Obstetrics and Gynecology, Denver, CO 9Tufts New England Medical Center, Department of Obstetrics and Gynecology, Boston, MA 10New York University Medical Center, Obstetrics and Gynecology, New York, NY 11Women and Infants Hospital, Department of Obstetrics and Gynecology, Providence, RI 12University of North Carolina at Chapel Hill, Department of Obstetrics and Gynecology, Chapel Hill, NC 13DM Stat, Medford, MA
        Saturday, February 7, 2004
        8:00am to 10:00amOral Concurrent Session 5Grand Ball Room A
        Epidemiology/Genetics/Ultrasound
        Moderators: Robin Field, MD
        Michael L. Socol, MD
        8:0053THE ASSOCIATION BETWEEN FIRST-TRIMESTER MATERNAL SERUM PAPP-A AND FREE BETA-HCG CONCENTRATIONS AND OBSTETRIC COMPLICATIONS: A POPULATION-BASED SCREENING STUDY (THE FASTER TRIAL)Lorraine Dugoff,1 John Hobbins,2 Fergal Malone,3 T. Porter,4 David Luthy,5 Christine Comstock,6 Gary Hankins,7 Richard Berkowitz,8 Irwin Merkatz,9 Sabrina Craigo,10 Ilan Timor,11 Stephen Carr,12 Honor Wolfe,13 Nicole Tibbetts,14 Mary D'Alton,151University of Colorado Health Sciences Center, Obstetrics and Gynecology, Denver, CO 2University of Colorado Health Sciences Center, Pediatrics, Denver, CO 3Columbia University, Obstetrics and Gynecology, New York, NY 4University of Utah, Obstetrics and Gynecology, Salt Lake City, UT 5Pediatrix/Obstetrix Medical Group, Seattle, WA 6William Beaumont Medical Center, Beaumont, MI 7University of Texas Medical Branch at Galveston, Obstretics & Gynecology, Galveston, TX 8Mount Sinai, New York, NY 9Albert Einstein College of Medicine, ob/gyn, New York, NY 10Tufts University, Obstetrics/Gynecology, Boston, MA 11New York University, Obstetrics and Gynecology, New York, NY 12Brown University, Providence, RI 13Wayne State University, Ob/Gyn/Maternal Fetal Med, Chapel Hill, NC 14dmstat, Boston, MA 15Columbia University, Maternal Fetal Medicine, New York, NY
        8:1554GENOME-WIDE EXPRESSION PROFILING OF FETAL MEMBRANES REVEALS DEFICIENT EXPRESSION OF PROTEINASE INHIBITOR 3 IN PREMATURE RUPTURE OF MEMBRANESGerard Tromp,1 Helena Kuivaniemi,2 Tinnakorn Chaiworapongsa,3 Yeon Mee Kim,3 Sam Edwin,3 Roberto Romero,31Wayne State University, Center for Molecular Medicine and Genetics, Detroit, MI 2Wayne State University, Surgery, Detroit, MI 3National Institute of Child Health and Human Development, Perinatology Research Branch, Detroit, MI
        8:3055THE HIGH-SECRETORY PHENOTYPE T ALLELE OF THE INTERLEUKIN (IL)-13 -1055 SINGLE-NUCLEOTIDE POLYMORPHISM DECREASES SUSCEPTIBILITY TO PRETERM LABOR (<32 WEEKS)Nina Mistry,1 Nicolas Orsi,1 Hilde Logghe,1 James Walker,1 Nigel Simpson,11University of Leeds, Academic Unit of Paediatrics, Obstetrics and Gynaecology, Leeds, England
        8:4556ELEVATED FIRST-TRIMESTER NUCHAL TRANSLUCENCY MEASUREMENT IS ASSOCIATED WITH AN INCREASED RISK OF CONGENITAL HEART DEFECTRay O. Bahado-Singh,1 Julia Zachary,2 Ronald J. Wapner, for the NICHD BUN Study Group,31University of Cincinnati, Obstetrics and Gynecology, Cincinnati, OH 2George Washington University, Biostatistics Center, Rockville, MD 3Drexel University College of Medicine, Philadelphia, PA
        9:0057THE QUAD SCREEN AS A PREDICTOR OF ADVERSE PREGNANCY OUTCOME: A POPULATION-BASED SCREENING STUDY (THE FASTER TRIAL)Lorraine Dugoff,1 John Hobbins,1 Fergal Malone,2 T. Porter,3 David Luthy,4 Christine Comstock,5 George Saade,6 Keith Eddleman,7 Irwin Merkatz,8 Sabrina Craigo,9 Ilan Timor,10 Stephen Carr,11 Honor Wolfe,12 Nicole Tibbetts,13 Mary D'Alton,21University of Colorado Health Sciences Center, Obstetrics and Gynecology, Denver, CO 2Columbia University, Maternal Fetal Medicine, New York, NY 3University of Utah, Obstetrics and Gynecology, Salt Lake City, UT 4Pediatrix/Obstetrix Medical Group, Seattle, WA 5William Beaumont Medical Center, Beaumont, MI 6University of Texas Medical Branch, Galveston, TX 7Mount Sinai School of Medicine, Obstetrics, Gynecology and Reproductive Science, New York, NY 8Albert Einstein College of Medicine, Ob/Gyn, New York, NY 9Tufts University, Obstetrics/Gynecology, Boston, MA 10New York University, Obstetrics and Gynecology, New York, NY 11Brown University, Providence, RI 12Wayne State University, Ob/Gyn/Maternal Fetal Med, Chapel Hill, NC 13DMSTAT, Boston, MA
        Saturday, February 7, 2004
        8:00am to 10:00amOral Concurrent Session 5Grand Ball Room A
        Epidemiology/Genetics/Ultrasound
        Moderators: Robin Field, MD
        Michael L. Socol, MD
        9:1558FIRST-TRIMESTER NASAL BONE EVALUATION FOR ANEUPLOIDY IN AN UNSELECTED GENERAL POPULATION: RESULTS FROM THE FASTER TRIALFergal D. Malone,1 Robert H. Ball,2 David A. Nyberg,3 Christine H. Comstock,4 George Saade,5 Richard L. Berkowitz,6 Susan J. Gross,7 Lorraine Dugoff,8 Sabrina D. Craigo,9 Ilan E. Timor,10 Stephen R. Carr,11 Honor M. Wolfe,12 Tara Tripp,13 Mary E. D'Alton,11Columbia University, New York, New York 2University of Utah, Salt Lake City, UT 3Swedish Medical Center, Seattle, WA 4William Beaumont Medical Center, Royal Oak, MI 5University of Texas Medical Branch, Galveston, TX 6Mount Sinai Medical Center, New York, New York 7Albert Einstein College of Medicine, New York, New York 8University of Colorado Health Sciences Center, Denver, CO 9Tufts University, Boston, MA 10New York University, New York, New York 11Brown University, Providence, RI 12UNC Medical Center, Chapel Hill, NC 13DM-Stat, Boston, MA
        9:3059MAINTAINING QUALITY ASSURANCE FOR NUCHAL TRANSLUCENCY SONOGRAPHY IN A PROSPECTIVE MULTICENTER STUDY: RESULTS FROM THE FASTER TRIALMary E. D'Alton,1 Fergal D. Malone,1 Geralyn Lambert-Messerlian,2 Robert H. Ball,3 David A. Nyberg,4 Christine H. Comstock,5 Radek Bukowski,6 Richard L. Berkowitz,7 Peer Dar,8 Lorraine Dugoff,9 Sabrina D. Craigo,10 Ilan E. Timor,11 Stephen R. Carr,2 Honor M. Wolfe,12 Tara Tripp,13 Jacob A. Canick,21Columbia University, New York, New York 2Brown University, Providence, RI 3University of Utah, Salt Lake City, UT 4Swedish Medical Center, Seattle, WA 5William Beaumont Medical Center, Royal Oak, MI 6University of Texas Medical Branch, Galveston, TX 7Mount Sinai Medical Center, New York, New York 8Albert Einstein College of Medicine, New York, New York 9University of Colorado Health Sciences Center, Denver, CO 10Tufts University, Boston, MA 11New York University, New York, New York 12UNC Medical Center, Chapel Hill, NC 13DM-Stat, Boston, MA
        9:4560AN INTERNATIONAL COLLABORATIVE STUDY OF ICSI 5-YEAR-OLDSUlla-Britt Wennerholm,1 Alastair Sutcliffe,2 Anne Loft,3 Maryse Bonduelle,4 Basil Tarlatzis,51Perinatal Center, Göteborg, 2Dep of Child Health, Royal Free Campus, London, 3Fertility Clinic, Copenhagen, 4Dept Medische Genetica, Brussels, 5Infertility and IVF Center, Thessaloniki
        Saturday, February 7, 2004
        8:00am to 10:00amOral Concurrnet Session 6Grand Ball Room B
        Infectious Disease/Neonatology/Prematurity
        Moderators: Washington C. Hill, MD
        Roberto Romero, MD
        8:0061GRAFTING OF GLIAL CELL LINE–DERIVED NEUROTROPHIC FACTOR-SECRETING CELLS FOR HYPOXIC-ISCHEMIC ENCEPHALOPATHY IN NEONATAL RATSShinji Katsuragi,1 Tomoaki Ikeda,1 Isao Date,2 Tetsurou Shingo,2 Takao Yasuhara,2 Tsuyomu Ikenoue,31Miyazaki Medical College, Obstetrics and Gynecology, Kiyotake Tyo, 2Okayama University Medical School, Neurological Surgery, Okayama City, 3Miyazaki Medical College, Obstetrics and Gynecology, Kiyotaketyou
        8:1562TUMOR NECROSIS FACTOR-α POLYMORPHISM -863 IN MOTHER-INFANT PAIRS AND INFLAMMATORY PRETERM BIRTHJosephine Amory,1 Kristina Adams,1 Ming-Tseh Lin,2 John Hansen,2 David Eschenbach,1 Jane Hitti,11University of Washington, Obstetrics and Gynecology, Seattle, WA 2Fred Hutchinson Cancer Research Center, Seattle, WA
        8:3063ELUCIDATING THE MECHANISMS BY WHICH PROGESTATIONAL AGENTS PREVENT PRETERM BIRTHMichal Elovitz,1 Zhao Wang,11University of Pennsylvania, Obstetrics and Gynecology, Philadelphia, PA
        8:4564IMPACT OF STEROID AND ANTIBIOTIC THERAPY IN THE SETTING OF INTRAUTERINE INFECTION ON DEVELOPMENT OF CNS LESIONS IN PREMATURE RABBIT FETUSPaul Gleason,1 Sreedhar Gaddipati,2 Alla Margita,1 Humayun Gultekin,3 Raffaella Morotti,3 Richard Berkowitz,2 Robert Lapinski,4 Ian Holzman,51Mount Sinai Medical Center, Obstetrics, Gynecology and Reproductive Sciences, New York, NY 2Columbia University, Obstetrics and Gynecology, New York, NY 3Mount Sinai Medical Center, Pathology, New York, NY 4Mount Sinai Medical Center, Community Medicine and Preventative Health, New York, NY 5Mount Sinai Medical Center, Pediatrics, New York, NY
        9:0065THE FREQUENCY AND CLINICAL SIGNIFICANCE OF INTRA-AMNIOTIC INFLAMMATION IN PATIENTS WITH PRETERM PREMATURE RUPTURE OF THE MEMBRANESSoon-Sup Shim,1Bo Hyun Yoon,1 Roberto Romero,1 Joon-Seok Hong,1 Gilja Kim,1 Yoo-Kyung Sohn,1 Joong Shin Park,1 Jong Kwan Jun,1 Hee Chul Syn,11Seoul National University, Dept. of Ob/Gyn, Seoul, Korea
        9:1566AMNIOTIC FLUID NITRIC OXIDE IS ASSOCIATED WITH AMNIOTIC APOPTOSIS AND INJURY IN INTRA-AMNIOTIC INFECTIONChaur-Dong Hsu,1 Stephanie Hong,1 Hassan Harirah,21New York Medical College–Westchester Medcial Center, Obstetrics and Gynecology, Valhalla, NY 2University of Texas Medical Branch at Galveston, OB/GYN, Galveston, TX
        9:3067HEMATOLOGIC INDICES AND FETAL OXYGENATION DETERMINE MIDDLE CEREBRAL ARTERY PEAK SYSTOLIC VELOCITY (MCA-PSV)Ahmet Baschat,1 Michelle Kush,1 Christopher Harman,1 Carl Weiner,21University of Maryland at Baltimore, Obstetrics, Gynecology and Reproductive Sciences, Baltimore, MD 2University of Maryland at Baltimore, Physiology, Baltimore, MD
        9:4568ANTIRETROVIRAL THERAPY IN PREGNANCY AND RISK OF ADVERSE PREGNANCY OUTCOMEAmanda Cotter,1 Adolfo Gonzalez Garcia,2 Lunthita Duthely,3 Mary J.O'Sullivan,41University of Miami, Dept of Ob/Gyn - MFM Division, Miami, FL 2University of Miami, Dept of Ob/Gyn-MFM Division, Miami, FL 3University of Miami, Dept Ob/Gyn, Miami, FL 4University of Miami, Dept Ob/Gyn-MFM Division, Miami, FL
        The March of Dimes Award for Best Research in Prematurity
        ∗∗ The Dru Carlson Memorial Award for Best Research in Ultrasound and Genetics
        ∗∗∗ Dr. Rodney Edwards is the SMFM 2001–2003 Scholarship Award recipient.