Abstract
Objective
This study was undertaken to evaluate the effect of a prenatal nutrition and education
program on twin pregnancy, neonatal, and early childhood outcomes.
Study design
This prospective intervention study of women who participated in a specialized program
(Program Pregnancies) versus nonparticipants included twice-monthly visits, dietary
prescription of 3000 to 4000 kcal per day, multimineral supplementation, and patient
education.
Results
Program Pregnancies were associated with improved pregnancy outcomes (preeclampsia,
adjusted odds ratio [AOR] 0.41, 95% CI, 0.23-0.75; preterm premature rupture of membranes,
AOR 0.35, 95% CI, 0.20-0.60; delivery <36 weeks, AOR 0.62, 95% CI, 0.43-0.89; low
birth weight, AOR 0.42, 95% CI, 0.29-0.61), significantly longer gestations (+7.6
days), higher birth weights (+220 g), lower neonatal morbidity (retinopathy of prematurity,
necrotizing enterocolitis, intraventricular hemorrhage, or ventilator support, AOR
0.44, 95% CI, 0.31-0.62), length of stay (–5.3 days), and cost per twin (–$14,023).
Through 3 years of age, program children were significantly less likely to be rehospitalized
(AOR 0.31, 95% CI, 0.11-0.91) or to be developmentally delayed (AOR 0.65, 95% CI,
0.44-0.96).
Conclusion
Program participation was associated with improved outcomes at birth and through age
3 years.
Keywords
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Article Info
Publication History
Miami, Fla, and Ann Arbor, Mich
Footnotes
☆Supported by grants from the Office of the Vice President for Research, University of Michigan, the Gerber Foundation, and Matria Healthcare, Inc.
☆Presented at the Twenty-Third Annual Meeting of the Society for Maternal-Fetal Medicine, San Francisco, Calif, February 3-8, 2003.
Identification
Copyright
© 2003 Mosby, Inc. Published by Elsevier Inc. All rights reserved.
