Abstract
Literature related to the prevalence and etiology of anticipatory nausea and vomiting
associated with chemotherapy is reviewed. Physiologic causes and psychological factors,
including expectations, beliefs, and conditioning, are examined to help explain these
phenomena. The efficacy of pharmacologic and behavioral treatments is discussed. Similarities
between the experience of anticipatory nausea and vomiting and morning sickness suggest
that the conditioning model may be relevant to understanding the development of pregnancy-related
nausea. (Am J Obstet Gynecol 2002;186:S239-43.)
Keywords
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References
- Chemotherapy-induced nausea and vomiting. Easing patients' fear and discomfort with effective antiemetic regimens.Postgrad Med. 1993; 94: 55-58
- Nausea and vomiting remain a significant clinical problem: trends over time in controlling chemotherapy-induced nausea and vomiting in 1413 patients treated in community clinical practices.J Pain Symptom Manage. 2000; 20: 113-121
- Conditioned aversive responses in cancer chemotherapy patients: theoretical and developmental analysis.J Consult Clin Psychol. 1986; 54: 593-600
- Hyperemesis gravidarum.Gastroenterol Clin N Am. 1992; 21: 835-849
- Anticipatory nausea and vomiting: Models, mechanisms and management. Martin Dunitz, London1997: 149-166
- Nausea and vomiting in pregnancy.J Soc Obstetricians and Gynaecologists Can. 1994; 16: 2035-2041
- Gastric dysrhythmias and nausea of pregnancy.Dig Dis Sci. 1990; 35: 961-968
- Textbook for midwives.in: Churchill-Livingstone, New York1975: 124
- Williams' obstetrics.in: Appleton-Century-Crofts, New York1980: 322-323
- Managing chemotherapy-related nausea and vomiting: the state of the art.Oncol Nurs Forum. 1989; 16: 563-574
- Anticipatory nausea and vomiting in cancer patients.J Consult Clin Psychol. 1991; 59: 894-898
- Antiemetic efficacy of high-dose metoclopramide: randomized trials with placebo and prochlorperazine in patients with chemotherapy-induced nausea and vomiting.N Engl J Med. 1981; 305: 905-909
- Nausea and vomiting.in: Holland JC Oxford University Press, New York1998: 476-484
- Nausea and vomiting in pregnancy: a review of the problem with particular regard to psychological and social aspects.Br J Obstet Gynaecol. 1995; 102: 6-8
- Acupressure therapy for morning sickness. A controlled clinical trial.J Nurse Midwifery. 1989; 34: 171-178
- Nonpharmacologic factors in the development of posttreatment nausea with adjuvant chemotherapy for breast cancer.Cancer. 1988; 61: 379-385
- Postchemotherapy nausea and vomiting in cancer patients receiving outpatient chemotherapy.J Psychosoc Oncol. 1991; 9: 117-130
- Expectation and occurrence of postchemotherapy side effects: nausea and vomiting.Cancer Pract. 1995; 3: 247-253
- Patient expectations as predictor of chemotherapy-induced nausea.Ann Behav Med. 2000; 22: 121-126
- Development of anticipatory nausea: a prospective analysis.J Consult Clin Psychol. 1985; 53: 447-454
- The development of anticipatory nausea in patients receiving adjuvant chemotherapy for breast cancer.Physiol Behav. 1997; 61: 737-741
- Cardiovascular conditioning and anticipatory nausea and vomiting in cancer patients.Behav Med. 1994; 20: 78-173
- A longitudinal study of the development of anticipatory nausea and vomiting in cancer chemotherapy patients: the role of absorption and autonomic perception.Health Psychol. 1992; 11: 181-189
- Conditioned nausea after cancer chemotherapy and autonomic nervous system conditionability.Scand J Psychol. 1993; 34: 318-327
- Etiology and treatment of the psychological side effects associated with cancer chemotherapy: a critical review and discussion.Psychol Bull. 1988; 104: 307-325
- Predicting development of anticipatory nausea in cancer patients: prospective examination of eight clinical characteristics.J Pain Symptom Manage. 1991; 6: 215-223
- Chemotherapy-related nausea and vomiting: etiology and management.Ca Cancer J Clin. 1989; 39: 89-104
- The role of anxiety in the development of anticipatory nausea in cancer chemotherapy: a review and synthesis.Psychosom Med. 1990; 52: 458-475
- The pharmacology and clinical effectiveness of phenothiazines and related drugs for managing chemotherapy-induced emesis.Drugs. 1983; 25: 35-51
- Inhibition of cisplatin-induced vomiting by selective 5-hydroxytryptamine M-receptor antagonism.Br J Pharmacol. 1986; 88: 497-499
- NCCN Proceedings. NCCN antiemesis practice guidelines.Oncology (Huntingt). 1997; 11: 57-89
- Ondansetron compared with high-dose metoclopramide in prophylaxis of acute and delayed cisplatin-induced nausea and vomiting.Ann Intern Med. 1990; 113: 834-840
- Comparison of the 5-hydroxytryptamine (serotonin) antagonist ondansetron (GR 38032F) with high-dose metoclopramide in the control of cisplatin-induced emesis.New Engl J Med. 1990; 322: 816-821
- Progress in reducing anticipatory nausea and vomiting: a study of community practice.Support Care Cancer. 1998; 6: 46-50
- Anticipatory nausea and vomiting with chemotherapy.N Engl J Med. 1982; 306: 431-432
- Efficacy and safety of granisetron, a selective 5-hydroxytryptamine-3 receptor antagonist, in the prevention of nausea and vomiting induced by high-dose cisplatin.J Clin Oncol. 1994; 12: 2204-2210
- Behavioral treatment for the anticipatory nausea and vomiting induced by cancer chemotherapy.N Engl J Med. 1982; 307: 1476-1480
- Comparing the effectiveness of behavioral treatment for chemotherapy-induced nausea and vomiting when administered by oncologists, oncology nurses, and clinical psychologists.Health Psychol. 1992; 11: 250-256
- Posttreatment use of relaxation training by cancer patients.Hosp J. 1988; 4: 1-8
- Effectiveness of biofeedback and relaxation training in reducing the side effects of cancer chemotherapy.Health Psychol. 1992; 11: 17-23
- Effects of coping style and relaxation on cancer chemotherapy side effects and emotional responses.Cancer Nurs. 1990; 13: 308-315
- Effectiveness of relaxation training in reducing the aversiveness of chemotherapy in the treatment of cancer.J Behav Ther Exp Psychiatry. 1979; 10: 357-361
- Effect of the cognitive hierarchy in the systematic desensitization treatment of anticipatory nausea in cancer patients: a component comparison with relaxation only, counseling, and no treatment.Cogn Ther Res. 1986; 10: 421-446
- Behavioral intervention in cancer treatment: controlling aversion reactions to chemotherapy.J Consult Clin Psychol. 1982; 50: 1018-1029
- The treatment of hyperemesis gravidarum with hypnotherapy.Am J Obstet Gynecol. 1957; 73: 444-447
- The psychosomatic treatment of hyperemesis gravidarum by hypnosis.Am J Obstet Gynecol. 1946; 51: 544-552
- Self-hypnosis as antiemetic therapy in children receiving chemotherapy.Oncol Nurs Forum. 1985; 12: 41-46
- The use of self-hypnosis by children with cancer.Am J Clin Hypn. 1975; 17: 233-238
- Hypnosis for reduction of vomiting associated with chemotherapy and disease in adolescents with cancer.J Adolesc Health Care. 1983; 4: 77-84
- Effects of video games on the adverse corollaries of chemotherapy in pediatric oncology patients: a single-case analysis.J Consult Clin Psychol. 1985; 53: 223-228
- Cognitive/attentional distraction in the control of conditioned nausea in pediatric cancer patients receiving chemotherapy.J Consult Clin Psychol. 1987; 55: 391-395
- Emesis in anti-cancer therapy. Mechanisms and treatment. Chapman and Hall Medical, London1993
- Behavioural interventions and psychological aspects of care during chemotherapy.Eur J Cancer. 1992; 28A: S39-S41
- Patients' pretreatment expectations of chemotherapy-related nausea are an independent predictor of anticipatory nausea.Ann Behav Med. 1998; 20: 104-109
Article info
Footnotes
☆Reprint requests: Sara Matteson, University of Rochester Cancer Center, Behavioral Medicine Unit, 601 Elmwood Ave, Box 704, Rochester, New York 14642. E-mail: [email protected]
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© 2002 Published by Elsevier Inc.
