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Comparison of adenocarcinoma and squamous cell carcinoma of the uterine cervix: A population-based epidemiologic study

  • Author Footnotes
    a From the Epidemiology Program, Department of Medicine, and the Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, College of Medicine, University of California, Irvine.
    Hoda Anton-Culver
    Correspondence
    Reprint requests: Hoda Anton-Culver, PhD, Epidemiology Program, Department of Medicine, University of California, Irvine, Irvine, CA 92717.
    Footnotes
    a From the Epidemiology Program, Department of Medicine, and the Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, College of Medicine, University of California, Irvine.
    Affiliations
    Irvine, California
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  • Author Footnotes
    a From the Epidemiology Program, Department of Medicine, and the Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, College of Medicine, University of California, Irvine.
    Jeffrey D. Bloss
    Footnotes
    a From the Epidemiology Program, Department of Medicine, and the Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, College of Medicine, University of California, Irvine.
    Affiliations
    Irvine, California
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  • Author Footnotes
    a From the Epidemiology Program, Department of Medicine, and the Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, College of Medicine, University of California, Irvine.
    Deborah Bringman
    Footnotes
    a From the Epidemiology Program, Department of Medicine, and the Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, College of Medicine, University of California, Irvine.
    Affiliations
    Irvine, California
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  • Author Footnotes
    a From the Epidemiology Program, Department of Medicine, and the Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, College of Medicine, University of California, Irvine.
    Anna Lee-Feldstein
    Footnotes
    a From the Epidemiology Program, Department of Medicine, and the Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, College of Medicine, University of California, Irvine.
    Affiliations
    Irvine, California
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  • Author Footnotes
    a From the Epidemiology Program, Department of Medicine, and the Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, College of Medicine, University of California, Irvine.
    Philip DiSaia
    Footnotes
    a From the Epidemiology Program, Department of Medicine, and the Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, College of Medicine, University of California, Irvine.
    Affiliations
    Irvine, California
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  • Author Footnotes
    a From the Epidemiology Program, Department of Medicine, and the Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, College of Medicine, University of California, Irvine.
    Alberto Manetta
    Footnotes
    a From the Epidemiology Program, Department of Medicine, and the Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, College of Medicine, University of California, Irvine.
    Affiliations
    Irvine, California
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  • Author Footnotes
    a From the Epidemiology Program, Department of Medicine, and the Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, College of Medicine, University of California, Irvine.
      This paper is only available as a PDF. To read, Please Download here.
      OBJECTIVE: Our objective was to compare epidemiologic and clinical characteristics of adenocarcinoma with those of squamous cell carcinoma of the cervix, with respect to risk by ethnic group, age at diagnosis, stage of disease at diagnosis, and survival.
      STUDY DESIGN: All data were obtained from the Cancer Surveillance Program of Orange County, California, from 1984 through 1989. A total of 152 cases of adenocarcinoma and 457 of squamous cell carcinoma of the uterine cervix were included.
      RESULTS: Adenocarcinoma of the cervix was diagnosed at a younger age and an earlier stage than squamous cell carcinoma. Hispanics have the highest risk for squamous cell carcinoma, whereas Asians have the highest risk for adenocarcinoma compared with whites. No differences were observed between the two histologic types in prognosis and survival.
      CONCLUSION: Differences between the two histologic types of cervix cancer were found in the age at diagnosis, the extent of disease, and the ethnic distribution. In spite of these differences, prognosis and survival were not affected by histologic type.

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