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Summary
We tested the feasibility of photocoagulating placental vascular communications with
a fetoscopically delivered neodymium:yttrium-aluminum-garnet laser in 12 pregnant
monkeys in the second trimester. The technique was successful in eight cases. One
ended in spontaneous labor 2 weeks after occlusion and one stillbirth occurred at
term. Six live fetuses were delivered at term, with all treated vessels demonstrating
occlusion. There was minimal placental damage at the laser impact sites, and no fetal
abnormalities were detected. Long-term occlusion of placental vasculature can be accomplished
by fetoscopically delivered laser energy. (Am J Obstet Gynecol 1989;160:485-9.)
Keywords
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References
- Multiple pregnancy (first of two parts).N Engl J Med. 1973; 288: 127-184.
- The pathology of the human placenta.in: Springer-Verlag, New York1974: 212-213.
- Fetoscope-directed neodymium-YAG laser: a potential tool for fetal surgery.Am J Obstet Gynecol. 1983; 145: 379-380.
- Treatment of placental vasculature with a neodymium-YAG laser via fetoscopy.Am J Obstet Gynecol. 1985; 151: 1126-1127.
- Gross anatomy of the placenta of rhesus monkeys.Obstet Gynecol. 1970; 36: 167-177.
- Histologic and ultrastructural changes in rhesus monkey placenta following interruption of fetal placental circulation by fetectomy or interplacental umbilica.Acta Anat. 1972; 81: 481-506.
- Antenatal diagnosis of twin transfusion syndrome by ultrasound.Obstet Gynecol. 1981; 58: 123-127.
Article info
Publication history
Accepted:
August 1,
1988
Received in revised form:
June 22,
1988
Received:
July 2,
1987
Footnotes
This study was supported by National Institutes of Health grants 507-RR05428 and RR00169.
Identification
Copyright
© 1989 Mosby. Published by Elsevier Inc. All rights reserved.
