A comparative histologic study on the healing process after tissue transection

II. Carbon dioxide laser and surgical microscissors
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      In a previous study we have demonstrated that tissue transaction with a carbon dioxide laser produces less carbon and less foreign body reaction than electromicrosurgery. The purpose of this study was to compare the healing process subsequent to transection of the rat uterine horn with carbon dioxide laser and microscissors. Incisions were histologically examined on postoperative days 0, 4, 10, 14, and 21. The following histologic parameters were assessed: scar width; amount of carbon and necrotic debris; number of polymorphonuclear leukocytes, lymphocytes, histiocytes, and giant cells; and extent of edema, exudate, and collagen in the scar. The results show that cutting with a carbon dioxide laser causes significantly more necrosis and hence more extensive foreign body reaction than cutting with microscissors. (Am J Obstet Gynecol 1989;160:1068-72.)

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        • Diamond DD
        • Daniell JF
        • Martin DC
        • et al.
        Tubal patency and pelvic adhesions at early second look laparoscopy following intra-abdominal use of the carbon dioxide laser: initial report of the intra-abdominal laser study group.
        Fertil Steril. 1984; 42: 717
        • Mage G
        • Bruhat MA
        Pregnancy following salpingostomy: comparison between C02 laser and electrosurgery procedures.
        Fertil Steril. 1983; 40: 472
        • Tulandi T
        • Vilos GA
        A comparison between laser surgery and electrosurgery for bilateral hydrosalpinx: a two-year follow-up.
        Fertil Steril. 1985; 44: 846
        • Kelly RN
        • Roberts DK
        Experience with the carbon dioxide laser in gynecologic microsurgery.
        Am J Obstet Gynecol. 1985; 146: 585
        • Daniell JF
        • Herbert SM
        Laparoscopic salpingostomy utilizing the C02 laser.
        Fertil Steril. 1984; 41: 558
        • Baggish MS
        • Chong AP
        Carbon dioxide laser microsurgery of the uterine tube..
        Obstet Gynecol. 1981; 58: 111
        • Choe JK
        • Dawood MY
        • Bordawil WA
        • et al.
        Clinical and histologic evaluation of laser reanastomosis of the uterine tube.
        Fertil Steril. 1984; 41: 754
        • Bellina JH
        • Hemmings R
        • Voros JI
        • et al.
        Carbon dioxide laser and electrosurgical wound study with an animal model: a comparison of tissue damage and healing patterns in peritoneal tissue.
        Am J Obstet Gynecol. 1984; 148: 327
        • Fayez JA
        • McComb JS
        • Harper MM
        Comparison of tubal surgery with the C02 laser and unipolar microelectrodes.
        Fertil Steril. 1983; 40: 476
        • Montgomery TC
        • Sharp JB
        • Bellina H
        • et al.
        Comparative gross and histological study of the effects of scalpel, electric knife and carbon dioxide laser on skin and uterine incisions in dogs.
        Lasers Surg Med. 1983; 3: 9
        • Filmar S
        • Jetha N
        • McComb P
        • Gomel V
        A comparative histologic study on the healing process following tissue transection: Part 1. C02 laser and electromicrosurgery..
        Am J Obstet Gynecol. 1989; : 160
        • Gomel V
        Microsurgical reversal of female sterilization: reappraisal.
        Fertil Steril. 1980; 33: 387
        • Gomel V
        Microsurgery in female infertility. Little, Brown, and Co., Boston1983: 147 (171, 183)
        • Bellina JH
        • Bandieramonte G
        Principles and practice of gynecologic laser surgery. Plenum Medical Book, New York1984: 202
        • Grunert GM
        Carbon dioxide laser in tubal microsurgery. [Letter].
        Am J Obstet Gynecol. 1984; 148: 117
        • Swolin K
        Microsurgical correction of distal tubal occlusion. Presented at the Sixth International Workshop on Microsurgery in Gynecology, Vancouver, British Columbia. 1984
        • Lehmann EL
        Nonparametrics: statistical methods based on ranks. Holden-Day Inc., 1975
        • Filmar S
        • Gomel V
        • McComb P
        The effectiveness of CO, laser and electromicrosurgery in adhesiolysis: a comparative study.
        Fertil Steril. 1986; 45: 407