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A comparative histologic study on the healing process after tissue transection

I. Carbon dioxide laser and electromicrosurgery
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      Abstract

      The present study was undertaken to evaluate and compare histologic parameters of wound healing subsequent to a standard uterine incision with carbon dioxide laser and electromicrosurgery in the rat model. The following histologic parameters were assessed and scored: scar width; amount of particulate carbon and necrotic debris; number of polymorphonuclear leukocytes, lymphocytes, histiocytes, and giant cells; and extent of edema, exudate, and collagen in the scar. The incisions were evaluated on postoperative days 0, 4, 7, 14, and 21. The ensuing scars were similar with respect to scar width and the amount of collagen in the scar. Foreign body reaction, denoted by histiocytes and giant cells, was significantly more pronounced in the electromicrosurgery group. Carbon particles, along with necrotic debris, appear to induce a foreign body tissue reaction. The particulate carbon in the electromicrosurgical incisions was significantly more extensive and was associated with the pronounced and longer lasting foreign body reaction in this group. (AM J OssTET GYNECOL 1989;160:1062-7.)

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      References

        • Kaplan I
        • Goldman J
        • Ger R
        The treatment of erosions of the uterine cervix by means of the CO, laser.
        Obstet Gynecol. 1973; 41: 795
        • Diamond DD
        • Daniell JF
        • Martin DC
        • et al.
        Tubal patency and pelvic adhesions at early second look laparoscopy following intra-abdominal use of the carbon dioxide laser: initial report of the intra-abdominal laser study group.
        Fertil Steril. 1984; 42: 717
        • Mage G
        • Bruhat MA
        Pregnancy following salpingostomy: comparison between CO, laser and electrosurgery procedures.
        Fertil Steril. 1983; 40: 472
        • Tulandi T
        • Vilos GA
        A comparison between laser surgery and electrosurgery for bilateral hydrosalpinx: a two-year followup.
        Fertil Steril. 1985; 44: 846
        • Kelly RN
        • Roberts DK
        Experience with the carbon dioxide laser in gynecologic microsurgery.
        AM J OBSTE`r GvNECOL. 1985; 146: 585
        • Daniell JF
        • Herbert SM
        Laparoscopic salpingostomy utilizing the CO, laser.
        Fertil Steril. 1984; 41: 558
        • Baggish MS
        • Chong AP
        Carbon dioxide laser microsurgery of the uterine tube..
        Obstet Gynecol. 1981; 58: 111
        • Choe JK
        • Dawood MY
        • Bordawil WA
        • et al.
        Clinical and histologic evaluation of laser reanastomosis of the uterine tube.
        Fertil Steril. 1984; 41: 754
        • Bellina JH
        • Hemmings R
        • Voros JI
        • et al.
        Carbon dioxide laser and electrosurgical wound study with an animal model: a comparison of tissue damage and healing patterns in peritoneal tissue.
        Am J Obstet Gynecol. 1984; 148: 327
        • Fayez JA
        • McComb JS
        • Harper MM
        Comparison of tubal surgery with the COZ laser and unipolar microelectrodes.
        Fertil Steril. 1983; 40: 476
        • Montgomery TC
        • Sharp JB
        • Bellina JH
        • et al.
        Comparative gross and histological study of the effects of scalpel, electric knife and carbon dioxide laser on skin and uterine incisions in dogs.
        Lasers Surg Med. 1983; 3: 9
        • Gomel V
        Microsurgery in female infertility. Little, Brown & Co, Boston1983: 147
        • Lehmann EL
        Nonparametrics: statistical methods based on ranks. Holden-Day, San Francisco1975