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Uterine fluid and prolactin secretion in the ovulating cynomolgus monkey

  • Yu-Kang Ying
    Correspondence
    Reprint requests: Yu-Kang Ying, M.D., Department of Obstetrics and Gynecology, Nassau County Medical Center, SUNY at Stony Brook, 2201 Hempstead Turnpike, East Meadow, NY 11554.
    Affiliations
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Connecticut Health Center Farmington, Connecticut USA.
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  • John F. Randolph
    Affiliations
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Connecticut Health Center Farmington, Connecticut USA.
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  • Donald B. Maier
    Affiliations
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Connecticut Health Center Farmington, Connecticut USA.
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  • Sally T. Kuslis
    Affiliations
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Connecticut Health Center Farmington, Connecticut USA.
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  • Jane Chapitis
    Affiliations
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Connecticut Health Center Farmington, Connecticut USA.
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  • Daniel H. Riddick
    Affiliations
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Connecticut Health Center Farmington, Connecticut USA.
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      Abstract

      Immunoreactive prolactin is produced by late secretory human endometrium in vitro. Human myometrium in explant culture also produces prolactin. A primate model with the use of the cynomolgus monkey is described that allowed repeated samplings of uterine secretions in vivo. The uterine secretory prolactin thus measured appears immunoreactively similar to human serum prolactin, and the pattern of secretions reflects the previously described pattern of endometrial prolactin production in vitro.

      Keywords

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