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A sonographic sign for the detection in the second trimester of the fetus with Down's syndrome

  • Beryl R. Benacerraf
    Correspondence
    Reprint requests: Beryl R. Benacerraf, M.D., Director, Diagnostic Ultrasound Associates, 398B Brookline Ave., Boston, MA 02215.
    Affiliations
    Diagnostic Ultrasound Associates Harvard Medical School Boston, Massachusetts, USA

    the Department of Obstetrics and Gynecology, Harvard Medical School Boston, Massachusetts, USA

    Brigham, and Women's Hospital, Boston, Massachusetts, USA.
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  • Vanessa A. Barss
    Affiliations
    Diagnostic Ultrasound Associates Harvard Medical School Boston, Massachusetts, USA

    the Department of Obstetrics and Gynecology, Harvard Medical School Boston, Massachusetts, USA

    Brigham, and Women's Hospital, Boston, Massachusetts, USA.
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  • Lane A. Laboda
    Affiliations
    Diagnostic Ultrasound Associates Harvard Medical School Boston, Massachusetts, USA

    the Department of Obstetrics and Gynecology, Harvard Medical School Boston, Massachusetts, USA

    Brigham, and Women's Hospital, Boston, Massachusetts, USA.
    Search for articles by this author
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      Abstract

      Sonographic structural surveys were made at the time that 904 amniocenteses were performed for genetic evaluation in the second trimester. A sonographic sign was identified which places the fetus at high risk for having Down's syndrome.

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