Evaluation of a new tampon device for cytologic autocollection and mass screening of cervical cancer and its precursors

      This paper is only available as a PDF. To read, Please Download here.


      A new autocollection tampon device for obtaining material for cervical cytologic testing was compared with cervical scraping and endocervical aspiration in order to evaluate the cytodiagnostic results. In 1428 cases there proved to be a 94% correlation between these methods. In addition, both smears were compared in a group of patients known to have neoplastic disease of the cervix. In evaluating cervical cancer both techniques detected 100% of the cases. However, the smears, both regular and tampon, were able to diagnose only 96.5% and 89% of grade 3 lesions and 86% and 81% of grades 1 and 2 lesions, respectively. False negative results occurred in 8.2% of the regular smears and 15% of the tampon smear group. These preliminary data, if confirmed by more broad and in-depth studies, suggest the new autocollection tampon may be a useful tool for mass cervical screening.


      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to American Journal of Obstetrics & Gynecology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Papanicolaou GN
        • Traut HF
        The diagnostic value of vainal smears in carcinoma of the uterus.
        Am J Obstet Gynecol. 1941; 43: 193
        • Silverberg E
        Cancer statistics, 1979.
        Cancer. 1980; 30: 23-38
        • Cramer DW
        The role of cervical cytology in the declining morbidity and mortality of cervical cancer.
        Cancer. 1974; 34: 2018-2027
        • Rochat R
        The prevalence of cervical cancer screening in the United States in 1970.
        Am J Obstet Gynecol. 1976; 125: 478-483
        • Davis HJ
        The irrigation smear: accuracy in detection of cervical cancer.
        Acta Cytol. 1962; 6: 459-467
        • Carrow LA
        • Hilker RJ
        • Elesh RH
        • Eqqum PR
        Evaluation of the vaginal irrigation smear technique.
        Am J Obstet Gynecol. 1967; 97: 821-827
        • Mattingly RF
        • Boyd A
        • Frable WJ
        The vaginal irrigation smear: a positive method of cervical cancer control.
        Obstet Gynecol. 1967; 29: 463-470
        • Anderson WAD
        • Gunn SA
        Premalignant and malignant conditions of the cervix uteri: a tissue validity study of the vaginal irrigation smear method.
        Cancer. 1967; 20: 1587-1593
        • Richart RM
        • Vaillant HW
        The irrigation smear: false negative rates in a poulation with cervical neoplasia.
        JAMA. 1965; 192: 199-202
        • Reagan JW
        • Lin F
        An evaluation of the vaginal irrigation technique in the detection of uterine cancer.
        Acta Cytol. 1967; 11: 374-382
        • Papanicolaou GN
        Cytologic evaluation of smears prepared by the tampon method for the detection of carcinoma of the uterine cervix.
        Cancer. 1954; 7: 1185-1190
        • Bader GM
        • Simon TR
        • Koss LG
        • Day E
        A study of the detectron-tampon method as a screening device for uterine cancer.
        Cancer. 1956; 19: 332-337
        • Arata T
        • Sekiba K
        • Kato K
        Appraisal of self-collected cervical specimens in cytologic screening of uterine cancer.
        Acta Cytol. 1978; 22: 150-152
        • Maguchi M
        • Nakanishi M
        • Kato K
        Appraisal of a newly developed self-collection device for obtaining cervical specimens.
        Acta Cytol. 1982; 26: 633-635
        • Ishazuba Y
        • Oota K
        • Masubuchi K
        Practical cytodiagnosis.
        in: Igaku shoin, Tokyo1972: 223-232
        • Scott RB
        • Brown AM
        • Reagan JW
        Comparative results of the routine Papanicolaou and the Draghi tampon cytologic studies in atypical hyperplasia of the cervix and the uterine cervix.
        Am J Obstet Gynecol. 1957; 71: 349-353