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Abstract
From December 15, 1975 to June 16, 1980, 20 evaluable patients with International
Federation of Gynaecology and Obstetrics Stage I invasive adenocarcinoma of the ovary
were entered into a prospective study, including pretherapy restaging peritoneoscopy
followed by treatment with intraperitoneal chromic phosphate if there was no evidence
of residual macroscopic tumor. During a follow-up of 1½ to 6 years (median, 3 years
and 1 month), the survival rate without evidence of recurrent ovarian carcinoma was
95%. Moreover, there was a total absence of complications with the use of the sequential
steps of pretherapy peritoneoscopy, a normal preinjection peritoneogram, injection
of chromic phosphate in large volumes of solution, frequent change of position of
the patient after injection, and abdominal scans after injection. This method appears
to be safe and is associated with a significantly high survival rate.
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References
- Effects of injection volume on the tissue dose, dose rate, and therapeutic potential of intraperitoneal P32.Radiology. 1981; 1401: 193
- The role of radiation therapy in the management of ovarian carcinoma.Isr. J. Med. Sci. 1975; 13: 815
- Incidence of subclinical metastasis in Stage I and II ovarian carcinoma.Obstet. Gynecol. 1978; 52: 100
- Prophylactic use of radioactive gold in the treatment of primary ovarian cancer.Am. J. Obstet. Gynecol. 1966; 94: 766
- The effect of volume on the distribution of substances instilled into the peritoneal cavity.Gynecol. Oncol. 1978; 6: 106
- Radioactive colloids in the treatment of Stage I ovarian cancer.Obstet. Gynecol. 1972; 40: 42
- Radioactive chromic phosphate suspension: Studies on distribution, drug absorption, and effective therapeutic radiation in phantoms, dogs, and patients.Gynecol. Oncol. 1981; 12: 193
Article Info
Publication History
Accepted:
July 13,
1982
Received in revised form:
July 1,
1982
Received:
February 18,
1982
Identification
Copyright
© 1982 Published by Elsevier Inc.