Advertisement

Criteria for screening tests for gestational diabetes

      This paper is only available as a PDF. To read, Please Download here.

      Abstract

      A 50 gm, 1-hour glucose screening test was given to 381 gravid women 25 years of age or older. All women with plasma glucose values ≥130 mg/dl (119 mg/dl, whole blood) were given a 100 gm, 3-hour glucose tolerance test to diagnose gestational glucose intolerance using O'Sullivan's diagnostic criteria. On the basis of the distribution of screening test values, three diagnostic zones could be identified: a zone below 135 mg/dl plasma glucose, with less than 1% probability of diabetes; a zone above 182 mg/dl plasma glucose, with more than 95% probability of diabetes; and a central zone of uncertainty (135 to 182 mg/dl, plasma glucose), where further testing is required. These test results suggest that thresholds for further testing be lowered from 143 to 135 mg/dl of plasma glucose.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to American Journal of Obstetrics & Gynecology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Bleicher S.J.
        • O'Sullivan J.B.
        • Freinkl N.
        Carbohydrate metabolism in pregnancy. V. The interrelations of glucose, insulin and free fatty acids in late pregnancy and postpartum.
        N. Engl. J. Med. 1964; 271: 866
        • Burt R.L.
        Peripheral utilization of glucose in pregnancy. III. Insulin tolerance.
        Obstet. Gynecol. 1956; 2: 658
        • O'Sullivan J.B.
        • Charles D.
        • Mahan C.M.
        • Dandrow R.V.
        Gestational diabetes and perinatal mortality rate.
        Am. J. Obstet. Gynecol. 1973; 116: 901
        • O'Sullivan J.B.
        • Mahan C.M.
        • Charles D.
        • Dandrow R.V.
        Medical treatment of the gestational diabetic.
        Obstet. Gynecol. 1974; 43: 817
        • Coustan D.R.
        • Lewis S.B.
        Insulin therapy for gestational diabetes.
        Obstet. Gynecol. 1978; 51: 306
        • O'Sullivan J.B.
        • Mahan C.M.
        Criteria for the oral glucose tolerance test in pregnancy.
        Diabetes. 1964; 13: 278
        • O'Sullivan J.B.
        • Mahan C.M.
        • Charles D.
        • Dandrow R.V.
        Screening criteria for high-risk gestational diabetic patients.
        Am. J. Obstet. Gynecol. 1973; 116: 895
        • O'Sullivan J.B.
        Long-term follow-up of gestational diabetes.
        in: Camerini-Davalos R.A. Cole H.S. Early Diabetes. Academic Press, Inc.,, New York1975: 503-519
        • Merkatz I.E.
        • Duchon M.A.
        • Yamashita T.S.
        • Houser H.B.
        A pilot community-based screening program for gestational diabetes.
        Diabetes Care. 1980; 3: 453
        • Amankwah K.S.
        • Prentice R.L.
        • Fleury F.J.
        The incidence of gestational diabetes.
        Obstet. Gynecol. 1977; 49: 497
        • Mestman J.H.
        Outcome of diabetes screening in pregnancy and perinatal morbidity in infants of mothers with mild impairment in glucose tolerance.
        Diabetes Care. 1980; 3: 447
        • Gillmer M.D.G.
        • Oakley N.W.
        • Beard R.W.
        • Nithyananthan R.
        • Cawson M.
        Screening for diabetes during pregnancy.
        Br. J. Obstet. Gynaecol. 1980; 87: 377
        • Feinstein A.R.
        Clinical biostatistics: On the Sensitivity, Specificity and Discrimination of Diagnostic Tests.
        in: The C. V. Mosby Company, St. Louis1977: 214-228
        • Mager M.
        • Farese G.
        What is “true” about blood glucose? A comparison of three procedures.
        Am. J. Clin. Pathol. 1965; 44: 104
        • Henry E.J.
        ed. 1. Clinical Chemistry: Principles and Technics. Hoeber Medical (Harper & Row Publishers), New York1965: 651-652
        • National Diabetes Data Group
        Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance.
        Diabetes. 1979; 28: 1039