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Abstract
UABF and OABF were measured in dogs with the electromagnetic flowmeter. In eight nonpregnant
animals, UABF was on the average 3.2 ml/min and OABF 0.4 ml/min. In 10 pregnant bitches
near term UABF was 27.3 ml/min and OABF 1.3 ml/min. Complete aortic occlusion in the
pregnant bitch at term reduces UABF to 2.4 ml/min (loss of 24.9 ml/min) and increases
OABF to only 1.6 ml/min (gain of 0.3 ml/min). The conclusion is that most of the blood
flow to the uteroplacental unit in the pregnant bitch is channelled through the uterine
artery and the marked drop in UABF produced by acute aortic occlusion is not compensated
by an increase in OABF. The conditions are different in human pregnancy where the
progressive nature of the aortic compression by the pregnant uterus allows, under
the most favorable circumstances, the gradual development of a collateral circulation
mostly through the ovarian arteries. However, this does not occur all the time as
demonstrated by angiographic studies in a series of 12 patients and in similar studies
reported in the literature. This could result in a placental insufficiency.
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References
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Article Info
Publication History
Accepted:
June 8,
1979
Received in revised form:
June 1,
1979
Received:
January 19,
1979
Footnotes
☆The work was done at the I.R.M. Institute of the New York University School of Medicine, new York; Dr. F. E. Birkner, Director, Mario Clagnaz and Robert Kolwicz, Assistant Research Scientists.
Identification
Copyright
© 1980 Published by Elsevier Inc.
