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Quantitative bacteriology of the vaginal flora in vaginitis

  • Matthew E. Levison
    Correspondence
    Reprint requests: Matthew E. Levison, M.D., The Medical College of Pennsylvania, 3300 Henry Ave., Philadelphia, Pennsylvania 19129.
    Affiliations
    Department of Medicine The Medical College of Pennsylvania and Hospital, Philadelphia, Pennsylvania, USA

    Department of Obstetrics and Gynecology, The Medical College of Pennsylvania and Hospital, Philadelphia, Pennsylvania, USA
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  • Irwin Trestman
    Affiliations
    Department of Medicine The Medical College of Pennsylvania and Hospital, Philadelphia, Pennsylvania, USA

    Department of Obstetrics and Gynecology, The Medical College of Pennsylvania and Hospital, Philadelphia, Pennsylvania, USA
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  • Roseanna Quach
    Affiliations
    Department of Medicine The Medical College of Pennsylvania and Hospital, Philadelphia, Pennsylvania, USA

    Department of Obstetrics and Gynecology, The Medical College of Pennsylvania and Hospital, Philadelphia, Pennsylvania, USA
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  • Catherine Sladowski
    Affiliations
    Department of Medicine The Medical College of Pennsylvania and Hospital, Philadelphia, Pennsylvania, USA

    Department of Obstetrics and Gynecology, The Medical College of Pennsylvania and Hospital, Philadelphia, Pennsylvania, USA
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  • Claro N. Floro
    Affiliations
    Department of Medicine The Medical College of Pennsylvania and Hospital, Philadelphia, Pennsylvania, USA

    Department of Obstetrics and Gynecology, The Medical College of Pennsylvania and Hospital, Philadelphia, Pennsylvania, USA
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      Abstract

      Vaginal flora was studied quantitatively in 29 sexually active women, 16 to 33 years of age, to define the role ofC. vaginale in vaginitis. Seventeen were asymptomatic and 12 complained of symptoms of vaginitis. Seven asymptomatic women had scant secretions: four of these seven hadC. vaginale at log10 6 to 9 CFU per milliliter, none of whom had “clue” cells; none had trichomonas or candida; six had Lactobacilli at log10 7 to 9.7 per milliliter; only one had Bacteroidaceae at > log10 5 per milliliter. Ten asymptomatic women had easily collectable secretions; eight of 10 hadC. vaginale at log10 6.5 to 9.6 per milliliter, three of whom had “clue” cells; four had trichomonas and none candida; nine had Lactobacilli at log10 7 to 9.3 per milliliter; four had Bacteroidaceae at > log10 5 per milliliter. Twelve had vaginitis: five of 12 hadC. vaginale at log10 7.9 to 11 per milliliter, one of whom had “clue” cells; nine had either trichomonas or candida or both and three had no pathogen, includingC. vaginale; 10 had Lactobacilli at log10 7 to 10 per milliliter; six had Bacteriodaceae at >log10 5 per milliliter. Three had “clue” cells in absence ofC. vaginale.
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