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Tomographic diagnosis of pituitary microadenomas in Forbes-Albright syndrome (amenorrhea-galactorrhea)

  • Gilbert H. Cohen
    Correspondence
    Reprint requests: Gilbert H. Cohen, M.D., 3970 North 32 Terrace, Hollywood, Florida 33021.
    Affiliations
    Department of Neuroradiology, Wilford Hall USAF Medical Center Lackland Air Force Base, Texas, USA

    Department of Endocrinology, Wilford Hall USAF Medical Center Lackland Air Force Base, Texas, USA

    Department of Neurosurgery, Wilford Hall USAF Medical Center Lackland Air Force Base, Texas, USA
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  • Steven Dorfman
    Affiliations
    Department of Neuroradiology, Wilford Hall USAF Medical Center Lackland Air Force Base, Texas, USA

    Department of Endocrinology, Wilford Hall USAF Medical Center Lackland Air Force Base, Texas, USA

    Department of Neurosurgery, Wilford Hall USAF Medical Center Lackland Air Force Base, Texas, USA
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  • Christopher Norwood
    Affiliations
    Department of Neuroradiology, Wilford Hall USAF Medical Center Lackland Air Force Base, Texas, USA

    Department of Endocrinology, Wilford Hall USAF Medical Center Lackland Air Force Base, Texas, USA

    Department of Neurosurgery, Wilford Hall USAF Medical Center Lackland Air Force Base, Texas, USA
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      Abstract

      The present study documents a characteristic tomographic sellar abnormality in five patients with Forbes-Albright syndrome (ammenorrhea-galactorrhea) and surgically proved pituitary microadenomas. This abnormality, noted in patients with normal-sized sellae, consists of asymmetric erosion of the anterior inferior wall of the sella turcica. Utilizing the twin criteria of an elevated serum prolactin and characteristic sella abnormality, herein described, previously unrecognized patients with pituitary microadenomas can be diagnosed and treated effectively.
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