Antispermatozoal antibodies in infertile women with cervicovaginal schistosomiasis

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      An attempt has been made to detect antibodies against spermatozoa in sera of infertile women with cervicovaginal schistosomiasis. An agglutination technique was used. Positive agglutination tests were obtained in 63.4 per cent of infertile patients with cervicovaginal schistosomiasis compared to 10 per cent of patients with urinary or gastrointestinal schistosomiasis. In hepatic schistosomiasis, no agglutination was obtained. The antibodies detected were species but not individual specific. It is assumed that infestation of the cervix and/or vagina with Schistosoma stimulates the production of antispermatozoal antibodies or the formation of antibodies that have a cross-reaction to spermatozoa. These antibodies are most probably locally produced and then passed into the circulation.
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