Arias-stella phenomenon in spontaneous and therapeutic abortion

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      Endometrium from 100 abortions was examined histologically for evidence of the Arias-Stella phenomenon. This reaction was present in 78.9 per cent of spontaneous (predominantly incomplete) abortions and 81.3 per cent of therapeutic abortions, not a significant difference. This high incidence of the Arias Stelle phenomenon in therapeutic abortions is o Fered as a rebuttal to the suggestion that it appears only when there is disturbance of trophoblastic tissue, as in spontaneous abortion and ectopic pregnancy. Both the present study and other publications which are reviewed suggest that the Arias-Stella phenomenon is an exaggerated proliferative and secretory response to elevated hormonal levels, rather than an involutional and regressive sequel to fetal death.
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