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Abstract
Five hundred and fifty-seven patients with cervical dysplasia detected cytologically
were followed without biopsy or therapy to examine the natural history of the disease.
At the end of the follow-up period transition probabilities were calculated and transit
times of mild, moderate, and severe dysplasia to carcinoma in situ were computed.
These transit times ranged from a median of 86 months for patients with mild dysplasia
to 12 months for a patient with severe dysplasia. The median transit time to carcinoma
in situ for all dysplasias was 44 months.
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Article Info
Footnotes
☆This investigation was supported in part by United States Public Health Service Fellowship No. 5-K3-CA-13,975 and United States Public Health Service Research Grant No. CA-07060-06.
Identification
Copyright
© 1969 Published by Elsevier Inc.