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A follow-up study of patients with cervical dysplasia

  • Ralph M. Richart
    Affiliations
    Department of Pathology, College of Physicians and Surgeons, Columbia University New York, New York, USA

    Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University New York, New York, USA

    the Obstetrical and Gynecological Service (The Sloane Hospital) of the Presbyterian Hospital New York, New York, USA
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  • Bruce A. Barron
    Affiliations
    Department of Pathology, College of Physicians and Surgeons, Columbia University New York, New York, USA

    Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University New York, New York, USA

    the Obstetrical and Gynecological Service (The Sloane Hospital) of the Presbyterian Hospital New York, New York, USA
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      Abstract

      Five hundred and fifty-seven patients with cervical dysplasia detected cytologically were followed without biopsy or therapy to examine the natural history of the disease. At the end of the follow-up period transition probabilities were calculated and transit times of mild, moderate, and severe dysplasia to carcinoma in situ were computed. These transit times ranged from a median of 86 months for patients with mild dysplasia to 12 months for a patient with severe dysplasia. The median transit time to carcinoma in situ for all dysplasias was 44 months.
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