Prenatal serodiagnosis of blood group sensitization

II. Maternal sensitizations other than D(Rho), with a comparison of the red cell antigens Kell (K1), E(Rh″), and c(hr′)
      This paper is only available as a PDF. To read, Please Download here.


      All available prenatal sensitizations other than D (Rho) were examined by determining blood groups of all members in a pedigree; the newborn infants were studied for isoimmune erythroblastosis. The immune challenge responsible for the maternal sensitization was determined, and compatible blood for the mother and the infant was obtained in advance of delivery. Serologic types of erythroblastosis were detected that otherwise would have been unanticipated. Blood group sensitizations other than D (Rho) were compared in obstetric subjects and transfused male subjects. It is contended that the K (Kell) and E red cell antigens immunize persons chiefly through a series of incompatible transfusions and the c antigen through fetomaternal incompatible pregnancies—or rarely through both mechanisms. It is prudent transfusion practice to administer Kell- and E-compatible blood to patients lacking these antigens, especially to the multitransfused gravid woman.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to American Journal of Obstetrics & Gynecology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


      1. Bowman, H. S.: Am. J. Obst. & Gynec. In press.

        • Pirofsky B.
        Am. J. Obst. & Gynec. 1965; 92: 720
      2. Baltz, R., and Bowman, H. S.: Personal communication.

        • Giblett E.R.
        Clin. Obst. & Gynec. 1964; 7: 1044
        • Mollison P.L.
        ed. 4. Blood Transfusion in Clinical Medicine. Blackwell Scientific Publications, Oxford1967: 488-490
        • Allen Jr., F.H.
        • Warshaw A.L.
        Vox Sang. 1962; 7: 222
      3. Allen, F. H., Jr.: Personal communication.

        • Levine P.
        (Quoted by Race, R. R., and Sanger, R.)ed. 4. Blood Groups in Man. Blackwell Scientific Publications, Oxford1962: 338-339
        • Lostumbo M.M.
        • Holland P.V.
        • Schmidt P.J.
        New England J. Med. 1966; 275: 141
        • Mollison P.L.
        ed. 4. Blood Transfusion in Clinical Medicine. Blackwell Scientific Publications, Oxford1967: 345
      4. Perkins, H. A.: Personal communication.