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The fibrinolytic enzyme system in pregnancy

A comparison between ovarian and antecubital blood
  • Fritz K. Beller
    Footnotes
    Affiliations
    Department of Obstetrics and Gynecology, New York University Medical Center, New York, New York, USA

    Department of Medicine, New York University Medical Center, New York, New York, USA

    American National Red Cross Research Laboratory, New York University Medical Center, New York, New York, USA
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  • Gordon W. Douglas
    Affiliations
    Department of Obstetrics and Gynecology, New York University Medical Center, New York, New York, USA

    Department of Medicine, New York University Medical Center, New York, New York, USA

    American National Red Cross Research Laboratory, New York University Medical Center, New York, New York, USA
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  • Robert H. Morris
    Affiliations
    Department of Obstetrics and Gynecology, New York University Medical Center, New York, New York, USA

    Department of Medicine, New York University Medical Center, New York, New York, USA

    American National Red Cross Research Laboratory, New York University Medical Center, New York, New York, USA
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  • Alan J. Johnson
    Affiliations
    Department of Obstetrics and Gynecology, New York University Medical Center, New York, New York, USA

    Department of Medicine, New York University Medical Center, New York, New York, USA

    American National Red Cross Research Laboratory, New York University Medical Center, New York, New York, USA
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  • Author Footnotes
    ∗ Career Investigator of the Health Research Council of the City of New York under Contract 1–297.
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      Abstract

      The fibrinolytic enzyme system was evaluated from blood from antecubital veins, the inferior vena cava, and the ovarian veins in nonpregnant and pregnant women at term. The systemic fibrinolytic activity was decreased in pregnancy. No difference was found in plasminogen, plasmin, urokinase, and streptokinase inhibitor. In general, the activity was higher in ovarian veins than in the antecubital sample, both in pregnant and nonpregnant patients, which might be attributed to direct drainage from the activator-rich myometrium and Fallopian tubes.
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