Advertisement
AJOG Home
Advanced SearchSave search
Transactions of the Twenty-fourth Annual Meeting of the South Atlantic Association of Obstetricians and Gynecologists| Volume 84, ISSUE 7, P841-851, October 01, 1962

Myometrial and cardiovascular responses to alterations in plasma epinephrine and norepinephrine

DOI:https://doi.org/10.1016/0002-9378(62)90057-1
Myometrial and cardiovascular responses to alterations in plasma epinephrine and norepinephrine
Next ArticlePyophysometra exceeding one gallon
      This paper is only available as a PDF. To read, Please Download here.

      Abstract

      Plasma epinephrine and norepinephrine levels were determined when these hormones were separately infused into patients in labor.
      Norepinephrine caused increased incoordinate uterine activity and a pressor response. Epinephrine diminished uterine activity during spontaneous and oxytocin-induced labor. Increased tonus was noted in half the cases of spontaneous labor once the infusion was discontinued. The major cardiovascular response to epinephrine was depressor.
      When the infusion was discontinued, a rapid decrease in plasma hormone levels was seen and normal values were attained within 5 minutes. These plasma levels were correlated directly with uterine activity but not with the cardiovascular response which persisted for a longer period of time.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to American Journal of Obstetrics & Gynecology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Register: Create an account
      Institutional Access: Sign in to ScienceDirect

      References

        • Pose S.V.
        • Cibils L.A.
        • Zuspan F.P.
        Am. J. Obst. & Gynec. 1962; 84: 297
        • Cibils L.A.
        • Pose S.V.
        • Zuspan F.P.
        Am. J. Obst. & Gynec. 1962; 84: 307
        • Alvarez H.
        • Caldeyro-Barcia R.
        Arch. ginec. y obst. 1948; 7: 7
        • Caldeyro-Barcia R.
        • Alvarez H.
        J. Obst. & Gynaec. Brit. Emp. 1952; 59: 5
        • Hendricks C.H.
        Am. J. Obst. & Gynec. 1958; 76: 969
        • Caldeyro-Barcia R.
        • et al.
        J. Pharmacol. & Exper. Therap. 1957; 121: 18
        • Hendricks C.H.
        • Quilligan E.J.
        • Tyler C.W.
        • Tucker G.J.
        Am. J. Obst. & Gynec. 1959; 77: 1028
        • Lund A.
        Acta pharmacol. et toxicol. 1950; 6: 137
        • Price H.L.
        • Price M.L.
        J. Lab. & Clin. Med. 1957; 50: 769

      10. Zuspan, F. P.: Unpublished data.

        • Cohen G.
        • Goldenberg M.
        J. Neurochem. 1957; 2: 58
        • Cohen G.
        • Goldenberg M.
        J. Neurochem. 1957; 2: 71
        • Hochuli E.
        • Kaeser O.
        • Burger M.
        Experientia. 1957; 12: 71
        • Hochuli E.
        Geburtsh. u. Frauenh. 1960; 20: 835
        • Stone M.
        • Piliero S.J.
        • Hammer H.
        • Portnoy A.
        Obst. & Gynec. 1960; 16: 674
        • Manger W.M.
        • Wakim K.G.
        • Bollman J.
        ed. 1. Chemical Quantitation of Epinephrine and Norepinephrine in Plasma. Charles C Thomas, Publisher, Springfield, Ill1959: 289
        • Huntzinger W.A.
        • Ritzel G.
        • Staub H.
        Helvet. physiol. et pharmacol. acta. 1956; 14: c31
        • Cohen G.
        • Holland B.
        • Sha J.
        • Goldenberg M.
        J. Clin. Invest. 1959; 38: 1935
        • Israel S.L.
        • Stroup P.E.
        • Seligson H.T.
        • Seligson D.
        Obst. & Gynec. 1959; 14: 58
        • Ritzel G.
        • Staub H.
        • Huntzinger W.A.
        Deutsche med. Wchnschr. 1957; 82: 409
        • Bourne A.
        • Burn J.H.
        J. Obst. & Gynaec. Brit. Emp. 1927; 34: 249
        • Brown W.E.
        • Wilder V.M.
        Am. J. Obst. & Gynec. 1943; 45: 659
        • Woodbury R.A.
        • Abreu B.E.
        Am. J. Obst. & Gynec. 1944; 48: 406
        • Woodbury R.A.
        • Hamilton W.F.
        • Torpin R.
        Am. J. Physiol. 1938; 121: 640
        • Kaiser I.H.
        Surg. Gynec. & Obst. 1950; 90: 649
        • Kaiser I.H.
        • Harris J.S.
        Am. J. Obst. & Gynec. 1950; 59: 775
        • Garret W.J.
        J. Obst. & Gynaec. Brit. Emp. 1954; 61: 586
        • Reynolds S.R.M.
        • Harris J.S.
        • Kaiser I.H.
        ed. 1. Clinical Measurement of Uterine Forces in Pregnancy and Labor. Charles C Thomas, Publisher, Springfield, Ill1954
        • Ahlquist R.
        Am. J. Physiol. 1948; 153: 586
        • Johnson H.D.
        • Green H.D.
        • Lanier J.T.
        J. Pharmacol. & Exper. Therap. 1953; 108: 144
        • Green H.D.
        Am. J. Med. 1954; 17: 70

      Article Info

      Footnotes

      ☆Supported by Grants RG-8232 (cl) and in part by 666-M-13, H-1917 (c-5) from the National Institutes of Health, United States Public Health Service.

      ☆☆The Foundation Prize paper, presented at the Twenty-fourth Annual Meeting of the South Atlantic Association of Obstetricians and Gynecologists, Bal Harbor, Florida, Jan. 28–31, 1962.

      Identification

      DOI: https://doi.org/10.1016/0002-9378(62)90057-1

      Copyright

      © 1962 Published by Elsevier Inc.

      ScienceDirect

      Access this article on ScienceDirect
      We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the for this site.
      Copyright © 2022 Elsevier Inc. except certain content provided by third parties. The content on this site is intended for healthcare professionals.


      RELX