- 1.1. Three patients with histologically confirmed chorioadenoma destruens with extension and a patient with probable chorioadenoma were treated with amethopterin and all may be considered cured.
- 2.2. Twelve patients with histologically proved choriocarcinoma with metastases were treated with amethopterin. Five after 3 years are clinically normal. These represent a 41 per cent 3 year salvage. Four patients with choriocarcinoma with metastases, after repeated courses of amethopterin treatment, have shown considerable improvement but still show residual lesions during a follow-up of 1 to 2 years. Three patients died from drug toxicity during the course of this 3 year study.
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- Ann. New York Acac. Sc. 1960; 80: 283
- Proc. Soc. Exper. Biol. & Med. 93. 1956: 361
- J. A. M. A. 1958; 168: 845
- J. Nutrition. 1949; 38: 11
- Am. J. Obst. & Gynec. 1952; 63: 1298
☆Presented at the Pan-Pacific Surgical Association Congress, Honolulu, Hawaii, Sept. 27 1960.