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Mercurial diuretics in toxemia of pregnancy with sodium and potassium studies

  • Robert Craft Smith
    Affiliations
    Department of Obstetrics and Gynecology, Tulane University School of Medicine, New Orleans, La. USA

    the Division of Obstetrics and Gynecology, Tulane Unit, Charity Hospital of Louisiana at New Orleans New Orleans, La. USA
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  • James W. Hendrick
    Footnotes
    Affiliations
    Department of Obstetrics and Gynecology, Tulane University School of Medicine, New Orleans, La. USA

    the Division of Obstetrics and Gynecology, Tulane Unit, Charity Hospital of Louisiana at New Orleans New Orleans, La. USA
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  • Henry K. Miller
    Footnotes
    Affiliations
    Department of Obstetrics and Gynecology, Tulane University School of Medicine, New Orleans, La. USA

    the Division of Obstetrics and Gynecology, Tulane Unit, Charity Hospital of Louisiana at New Orleans New Orleans, La. USA
    Search for articles by this author
  • Author Footnotes
    ∗∗ Present address, 1529 Chaseville Road, Arlington, Jacksonville 11, Fla.
    ∗∗∗ Present address, 1629 Chaseville Road, Arlington, Jacksonville 11, Fla. ***Present address. 3369 Convention Street, Baton Rouge, La.
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      Abstract

      • 1.
        1. One hundred cases of pre-eclampsia in which mercurial diuretics were used in therapy are presented. Benefit, as evidenced by weight loss and/or increased urinary output, is evaluated.
      • 2.
        2. Sodium and potassium studies on blood and urine of 39 normal and 29 pre-eclamptic pregnant patients are reported, demonstrating:
        • 2.1.
          a. Almost identical lowered serum sodium levels in both these groups as compared to nonpregnant normal individuals.
        • 2.2.
          b. A decreased excretion of sodium and potassium in urine in both groups, especially marked in the pre-eclamptic patients.
      • 3.
        3. Studies of sodium and potassium in the blood and urine of 24 pre-eclamptic patients before and after receiving injections of a mercurial diuretic are reported, demonstrating a marked increase in sodium output after administration of the mercurial.
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