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A clinical study of premenstrual tension

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      Abstract

      A study of 249 volunteers with premenstrual symptoms at Westfield State Farm indicated that 51 per cent of the prison population (131 of 257 inmates), with an average age of 32.4 years, and 33 per cent of the reformatory population (118 of 358 inmates), with an average age of 21.4 years, suffered from premenstrual tension.
      Sugar tolerance tests showed a hypoglycemic-type curve in the premenstrual phase and premenstrual vaginal smears indicated hyperestrogenic stimulation.
      Review of the inmates' records indicated that 62 per cent of crimes of violence were committed in the premenstrual week.
      Therapy consisted of medication containing vitamin B complex and ammonium chloride, and supplementary feedings of milk and cheese in the premenstrual period. Analysis of the reported improvement indicates:
      15 per cent of inmates reported improvement when given placebos only
      39 per cent of inmates reported improvement with placebos plus supplementary high-protein diet;
      61 per cent of inmates reported improvement when given medication only
      79 per cent of inmates reported improvement when given medication plus supplementary high-protein diet.
      Medication in this phase of the study is held to be effective on symptoms of premenstrual tension rather than on the underlying estrogen-progesterone imbalance.
      Results showed increased work output, improvement in behavior and attitude, fewer requests for analgesic and sedative medication, less punishment for infraction of rules, and marked increase in the general morale.
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