Articles & Issues

Objectives: This study determined the influence of a 2-component polyethylene glycol surgical sealant (Coseal) as an adhesion prevention device on sepsis-related mortality and/or systemic bacterial tr...

Objective:: 17α-hydroxyprogesterone caproate (17P) may decrease risk of prematurity by suppressing maternal immunity. We hypothesized that in vivo 17P treatment attenuates immunoresponsiveness of peri...

Intestinal lymphangiectasia is an obstruction of the lymphatic system. We report on a patient with mesenteric adenopathy and an elevated CA125 level, which were suspicious for peritoneal carcinoma. Fu...

Objective:: We sought to determine the incidence of symptomatic deep venous thrombosis and pulmonary embolism, collectively referred to as venous thromboembolic events (VTE), in patients undergoing ur...

Objective: Endocervical curettage (ECC) specimens obtained during colposcopy can detect cervical cancer and precursors otherwise missed by biopsy alone, but the procedure can be painful and reduce com...

Objective:: We sought to compare sexual function and hormone concentrations in combined oral contraceptive (COC) and injectable progestin users. Study design:: Sexually active COC and depot medroxypro...

Objective:: The objective of the investigation was to study the association of fetal death with maternal age by length of gestation. Study Design:: This was a population study including all ongoing pr...

We appreciate the comments by Salomon et al regarding our analysis of the association of prenatal intraabdominal bowel dilation (IBD) with postnatal bowel complications. It is agreed that prenatal IBD...

We read with great interest the article by Huh et al, who reported their experience in the treatment of patients with a gastroschisis that was diagnosed antenatally. Their report concluded that prenat...

We report the association of gigantomastia during pregnancy and a lactating adenoma in ectopic breast tissue of the vulva in a context of myasthenia in a 27-year-old primigravid woman. We discuss the ...

The prevalence of obesity is growing among reproductive-age women. This is concerning because obesity has significant health-related consequences. Aside from the long-term risks of diabetes, heart dis...

Objective: The aim of this study was to estimate the number of women undergoing ambulatory surgical procedures for female pelvic floor disorders (PFDs) in the United States and to compare age-adjusted...

Objective: The objective of this review was to provide pooled estimates of randomized controlled trials comparing the effects of oral hypoglycemic agents with insulin in achieving glycemic control and...

Gestational trophoblastic neoplasia (GTN) includes invasive mole, choriocarcinoma, placental site trophoblastic tumor, and epithelioid trophoblastic tumor. The overall cure rate in treating these tumo...

Objective:: We sought to investigate the reproductive outcomes of women who underwent laparoscopic removal of benign cystic teratoma with or without intraoperative spillage. Study design:: The reprodu...

We recommended limiting the use of beta 2 adrenergic agonists (B2AA) to clearly proven indications consistent with American College of Obstetricians and Gynecologists recommendations. Due to the very ...

Witter et al suggest that beta adrenergic receptor agonists act as functional and behavioral teratogens and that use of these agents should be severely curtailed in pregnancy. The basis of this conclu...

Objective:: This analysis compared 3 continuous variables as summary support loss (SL) scores with pelvic organ prolapse (POP) quantification (POPQ) ordinal stages. Study design:: We used pooled basel...

Gestational trophoblastic disease includes hydatidiform mole (complete and partial) and gestational trophoblastic neoplasia (invasive mole, choriocarcinoma, placental site trophoblastic tumor, and epi...

Objective:: We sought to investigate the incidence of hip and proximal lower extremity pain following transobturator midurethral sling and evaluate the association between pain and body mass index (BM...

The rate of twin pregnancies in the United States has stabilized at 32 per 1000 births in 2006. Aside from determining chorionicity, first-trimester screening and second-trimester ultrasound scanning ...

First, we would like to thank Talaulikar and Manyonda for their valuable comments. The international trial of antioxidants in the prevention of preeclampsia was planned in 2001 and 2002 in response to...

We read with interest the results of the trial by Xu et al titled “An international trial of antioxidants in the prevention of preeclampsia (INTAPP).” This is the sixth large clinical trial that has f...

Objective: The purpose of this study was to evaluate the effect of maternal nifedipine on fetal survival when started 24-48 hours before selective fetoscopic laser photocoagulation (SFLP). Study desig...

Objective:: To describe the normative course of maternal sleep during the first 4 months postpartum. Study design:: Sleep was objectively measured using continuous wrist actigraphy. This was a longitu...

Objective: Most ultrasound estimated fetal weight (EFW) formulas incorporate abdominal circumference, which may overstimate growth restriction in fetal gastroschisis. The aim of this study was to dete...

Objective: During an uncomplicated pregnancy the conceptus is a semiallogeneic entity in which rejection is prevented by suppression of the maternal immune system. We hypothesized that this suppressio...

Objective: This study compared birth parameters and the longitudinal course in physical and neurologic development between children with 2 and 3 vessel umbilical cords. Study Design: Our study of the ...

Objective: This prospective randomized pilot study compared the use of the Ligaclip (Ethicon Endo-Surgery, Cincinnati, OH) with bipolar coagulation in preventing lymphoceles after laparoscopic pelvic ...

Objective:: Preeclampsia is associated with perinatal brain injury. Autologous placenta stem cell transplantation represents a promising future treatment option for neuroregeneration. The aim of this ...

Regarding the commentary by Witter et al, the authors go to great lengths to emphasize the possible risks and to dismiss the possible benefits of maintenance beta 2 agonist therapy in the management o...

We thank Dr Taslimi for his letter in regard to our study. We certainly agree with Dr Taslimi that investigators should be encouraged to research possible interventions for the prevention of preterm b...

The relatively small retrospective observational study by Fox et al is an example of diagnosis sans therapy that is prevalent in obstetric literature. A clinician's take-home message from this study i...

Objective:: We sought to evaluate amniotic fluid brain natriuretic peptide (BNP) levels as a biomarker of recipient twin (RT) cardiomyopathy (RTCM) in twin-twin transfusion syndrome. Study design:: Am...

Objective: Clinical evidence suggests that magnesium sulfate may reduce the risk of fetal neurologic injury in preterm delivery. Matrix metalloproteinase-9 (MMP-9) levels are elevated in preterm labor...

I have read with interest the recent “Clinical Opinion” in your February issue authored by Phelan and generally agree with her statements. However, the article is incomplete, not current, and did not ...

Dr Thornton's letter appropriately directs readers to her and her colleagues' well-designed randomized controlled trial examining the effects of an intervention to reduce excessive gestational weight ...

Objective: The objective of the study was to compare and contrast the effects of developmental hypoxia vs undernutrition on fetal growth, cardiovascular morphology, and function. Study Design: On day ...

Objective: We sought to assess pregnancy outcome along a continuum of cervical lengths (CLs) ≥25 mm. Study design: We conducted planned secondary analysis of a randomized cerclage trial of women with ...

Objective: Preimplantation factor is a novel embryo-derived peptide that influences key processes in early pregnancy implantation, including immunity, adhesion, remodeling, and apoptosis. Herein, we e...

OBJECTIVE: To describe contemporary cesarean delivery practice in the United States. STUDY DESIGN: Consortium on Safe Labor collected detailed labor and delivery information from 228,668 electronic me...

Objective: Women with twin pregnancies may have higher rates of isolated proteinuria than do those with singletons. We compared protein-to-creatinine (P:C) ratios longitudinally through gestation in u...

Objective: To determine preoperative predictive factors for donor and recipient death after laser ablation of placental vessels in twin-to-twin transfusion syndrome. Study Design: Retrospective analys...

Objective: The objective of the study was to isolate and characterize a population of mesenchymal stem cells (MSCs) from human term placental membranes. Study design: We isolated an adherent cell popu...

OBJECTIVE: Vitamin D deficiency has been linked to adverse pregnancy outcomes. The purpose of this investigation was to assess total 25-hydroxyvitamin D (25-OH-D) levels at diagnosis of early-onset se...

Objective: Docosahexaenoic acid (DHA) is a dietary fatty acid with neuroprotective properties. We hypothesized that DHA treatment after hypoxia-ischemia would improve function and reduce brain volume ...

Objective: To evaluate the screening accuracy of pregnancy hypertensive disorders by maternal serum biomarkers and uterine artery Doppler in the first trimester. Study Design: Prospectively enrolled n...

Objective: The purpose of this study was to assess myocardial function of fetuses who were exposed to intraamniotic infection compared with fetuses of uncomplicated pregnancies by the application of t...

Objective: The purpose of this study was to compare pre- and postoperative pelvic organ prolapse–quantification (POP-Q) and magnetic resonance imaging (MRI) measurements in patients who undergo total ...

Objective: To compare the indications for invasive prenatal testing resulting in the detection of translocation Down syndrome and complete trisomy 21. Study design: This case control study was based o...

Objective: The purpose of this study was to determine the impact of parity on mechanical behavior of the vagina and to correlate these findings with alterations in collagen structure. Study Design: Me...

Objective: To compare eclampsia and magnesium toxicity management among residents randomly assigned to lecture or simulation-based education. Study Design: Statified by year, residents (n = 38) were r...

Objective: Experimental data have revealed the critical role played by 2-methoxy-estradiol, a metabolite of 17β-estradiol, in the pathophysiology of preeclampsia. We used gas chromatography/mass spect...

Objective: The objective of the study was to evaluate allelic variation in 26 members of the solute carrier (SLC) gene family for an association with preeclampsia. Study Design: Preeclampsia cases wer...

Objective: The objective of the study was to measure the volumetric bone mineral density (vBMD) using diagnostic computed tomography scans in gynecologic oncology patients. Study Design: In a retrospe...

Objective: The objective of the study was to compare fetal venous Doppler flow reflecting cardiac function in fetuses with hydrops fetalis between a group of congenital heart defect (low cardiac outpu...

Objective: The purpose of this study was to evaluate the fetal mechanical PR interval in intrahepatic cholestasis of pregnancy (ICP). Study Design: Fetal echocardiography was performed for women with ...

Objective: We sought to determine whether maternal/fetal single-nucleotide polymorphisms (SNPs) in candidate genes are associated with preterm prelabor rupture of membranes (pPROM). Study design: A ca...

Objective: The purpose of this study was to determine the pregnancy outcome of asymptomatic patients in the second trimester with a nonmeasurable cervical length (0 mm). Study Design: This retrospecti...

Objective: The study objectives were to determine the surgical outcomes of a large series of gynecology patients treated with laparoendoscopic single-site surgery (LESS). Study design: This was a retr...