American Journal of Obstetrics & Gynecology
Volume 181, Issue 5, Supplement , Pages S39-S44 , November 1999

Efficacy and safety of a low-dose monophasic combination oral contraceptive containing 100 μg levonorgestrel and 20 μg ethinyl estradiol (Alesse®)

References 

  1. Arnt IC, Ferrari A, Sartoretto JN, Woutersz TB. Low-dose combination oral contraceptives: a controlled clinical study of three different norgestrel-ethinyl estradiol ratios. Fertil Steril. 1997;28:549–553
  2. Sartoretto JN, Ortega-Recio JC. Clinical evaluation of a low dosage estrogen-progesterone association (100 μg of d-norgestrel and 20 μg of ethinyl estradiol). Rev Bras Clin Ther. 1974;3:399–404
  3. Archer DF, Maheux R, DelConte A, O’Brien FB. A new low-dose monophasic combination oral contraceptive (Alesse) with levonorgestrel 100 μg and ethinyl estradiol 20 μg. North American Levonorgestrel Study Group (NALSG) Contraception. 1997;55:139–144
  4. Tietze C, Lewit S. Statistical evaluation of contraceptive methods. Clin Obstet Gynecol. 1974;17:121–138
  5. Schindler JF, Feldmann HU. 20 μg ethinylestradiol/100 μg levonorgestrel: mit dem neuen oralen contrazeptivum Miranova ist die palette levonorgestrel-haltiger ovulationshemmer vervollständigt worden. Gyne Extra. 1996;17:179–182
  6. Endrikat J, Müller U, Düsterberg B. A twelve-month comparative clinical investigation of two low-dose oral contraceptives containing 20 micrograms ethinylestradiol/75 micrograms gestodene and 30 micrograms ethinylestradiol/75 micrograms gestodene, with respect to efficacy, cycle control, and tolerance. Contraception. 1997;55:131–137
  7. Bannemerschult R, Hanker JP, Wünsch C, Fox P, Albring M, Brill K. A multicenter, uncontrolled clinical investigation of the contraceptive efficacy, cycle control, and safety of a new low oral contraceptive containing 20 micrograms ethinyl estradiol and 100 micrograms levonorgestrel over six treatment cycles. Contraception. 1997;56:285–290
  8. Speroff L, DeCherney A. Evaluation of a new generation of oral contraceptives. The Advisory Board for the New Progestins. Obstet Gynecol. 1998;81:1034–1047

 Supported by Wyeth-Ayerst Research, Philadelphia, Pa.

☆☆ Reprint requests: David F. Archer, MD, Jones Institute for Reproductive Medicine, Eastern Virginia Medical School, 601 Colley Ave, Norfolk, VA 23507-1627.

 0002-9378/99 $8.00 + 0 6/0/103094

PII: S0002-9378(99)70362-5

American Journal of Obstetrics & Gynecology
Volume 181, Issue 5, Supplement , Pages S39-S44 , November 1999