American Journal of Obstetrics & Gynecology
Volume 179, Issue 4 , Pages 879-883 , October 1998

Potential consequences of widespread antepartal use of ampicillin

Presented at the Eighteenth Annual Meeting of the Society of Perinatal Obstetricians, Miami, Florida, February 2-7, 1998.

References 

  1. Centers for Disease Control and Prevention . Prevention of perinatal group B streptococcal disease: a public health perspective. MMWR Morb Mortal Wkly Rep. 1996;45(RR-7):1–24
  2. American College of Obstetricians and Gynecologists . Prevention of early-onset group B streptococcal disease in newborns. Washington: The College; 1996; Committee Opinion No.: 173
  3. American Academy of Pediatrics . Revised guidelines for prevention of early-onset group B streptococcal (GBS) infection. Pediatrics. 1997;99:489–496
  4. Mercer BM, Miodovnik M, Thurnau GR, Goldenberg RL, Das AF, Ramsey RD, et al.  Antibiotic therapy for reduction of infant morbidity after preterm premature rupture of the membranes. JAMA. 1997;278:989–995
  5. Owen J, Groome LJ, Hauth JC. Randomized trial of prophylactic antibiotic therapy after preterm amnion rupture. Am J Obstet Gynecol. 1993;169:976–981
  6. American College of Obstetricians and Gynecologists . Preterm labor. Washington: The College; 1995; Technical Bulletin No.: 206
  7. McGregor JA, French JI, Reller LB, Todd JK, Makowski EL. Adjunctive erythromycin treatment for idiopathic preterm labor: results of a randomized, double-blinded, placebo-controlled trial. Am J Obstet Gynecol. 1986;154:98–103
  8. Meis PJ, Ernest JM, Moore ML. Causes of low birth weight births in public and private patients. Am J Obstet Gynecol. 1987;156:1165–1168
  9. Amon E, Lewis SV, Sibai BM, Villar MA, Arheart KL. Ampicillin prophylaxis in preterm premature rupture of the membranes: a prospective randomized study. Am J Obstet Gynecol. 1988;159:539–543
  10. Christmas JT, Cox SM, Andrews W, Dax J, Leveno KJ, Gilstrap LC. Expectant management of preterm ruptured membranes: effects of antimicrobial therapy. Obstet Gynecol. 1992;80:759–762
  11. McGregor JA, French JI, Seo K. Antimicrobial therapy in preterm rupture of membranes: results of a prospective, double-blind, placebo-controlled trial of erythromycin. Am J Obstet Gynecol. 1991;165:632–640
  12. McDuffie RS, McGregor JA, Gibbs RS. Adverse perinatal outcome and resistant enterobacteriaceae after antibiotic usage for premature rupture of the membranes and group B streptococcus carriage. Obstet Gynecol. 1993;82:487–489
  13. Mercer BM, Moretti ML, Prevost RR, Sibai BM. Erythromycin therapy in preterm premature rupture of the membranes: a prospective, randomized trial of 220 patients. Am J Obstet Gynecol. 1992;166:794–802
  14. Johnston MM, Sanchez-Ramos L, Vaughn AJ, Todd MW, Benrubi GI. Antibiotic therapy in preterm premature rupture of membranes: A randomized, prospective, double-blind trial. Am J Obstet Gynecol. 1990;163:743–747
  15. Amstey MS, Gibbs RS. Is penicillin G a better choice than ampicillin for prophylaxis of neonatal group B streptococcal infections?. Obstet Gynecol. 1994;84:1058–1059
  16. Stevens DC, Kleiman MB, Schreiner RL. Early-onset pseudomonas sepsis of the neonate. Perinatol Neonatol. 1982;6:75–77

☆ From University of California, Irvine,a Long Beach Memorial Women’s Hospital,b St Joseph’s Hospital,c the Department of Obstetrics and Gynecology, Medical College of Wisconsin,d Long Beach Memorial Miller Children’s Hospital.e

☆☆ Supported in part by the Memorial Medical Center Foundation, Long Beach, California. Research performed at Long Beach Memorial Women’s Hospital, Long Beach, California.

★ Reprint requests: Craig V. Towers, MD, PO Box 8400, Huntington Beach, CA 92615-8400.

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PII: S0002-9378(98)70182-6

American Journal of Obstetrics & Gynecology
Volume 179, Issue 4 , Pages 879-883 , October 1998

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