American Journal of Obstetrics & Gynecology
Volume 177, Issue 4 , Pages 959-963 , October 1997

External alkalinization decreases intracellular Ca++ and spontaneous contractions in pregnant rat myometrium

Received 20 February 1997 ,Accepted 5 June 1997.

References 

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  8. Taggart M, Wray S. Simultaneous measurement of intracellular pH and contraction in uterine smooth muscle. Pflugers Arch. 1993;423:527–529
  9. Taggart MJ, Burdyga T, Heaton RC, Wray S. Stimulus-dependent modulation of smooth muscle intracellular calcium and force by altered intracellular pH. Pflugers Arch Eur J Physiol. 1996;432:803–811
  10. Heaton RC, Wray S, Eisner DA. Effects of metabolic inhibition and changes of intracellular pH on potassium permeability and contraction of rat uterus. J Physiol. 1993;465:43–56
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  13. Khan RN, Smith SK, Morrison JJ, Ashford MLJ. Properties of large-conductance K+ channels in human myometrium during pregnancy and labour. Proc R Soc Lond B. 1993;251:9–15
  14. Wray S. Smooth muscle intracellular pH: measurement, regulation and function. Am J Physiol. 1988;254:C213–C225
  15. Parra J, Taggart MJ, Wray S. Functional effects of intracellular pH alteration in the human myometrium: simultaneous measurements of pH and force. J Reprod Fertil. 1995;105:71–75
  16. Wray S. Regulation of intracellular pH in rat uterine smooth muscle, studied by 31-phosphorus NMR spectroscopy. Biochim Biophys Acta. 1988;972:299–301
  17. Fry CH, Gallegos CRR, Montgomery BSI. The actions of extracellular H+ on the electrophysiological properties of isolated human detrusor smooth muscle cells. J Physiol. 1994;480:71–80
  18. Shmigol AV, Smith RD, Taggart MJ, Wray S, Eisner DA. Changes of pH affect calcium currents but not outward potassium currents in rat myometrial cells. Pflugers Arch Eur J Physiol. 1995;431:135–137

☆ From the Physiological Laboratory, University of Liverpool,a and the School of Biological Sciences, University of Manchester.b

☆☆ Supported by the Wellcome Trust, Royal Society, and Medical Research Council, United Kingdom.

★ Reprint requests: Susan Wray, PhD, Physiological Laboratory, Crown Street, University of Liverpool, Liverpool, L69 3BX, United Kingdom.

★★ 0002-9378/97 $5.00 + 0 6/1/83752

PII: S0002-9378(97)70301-6

American Journal of Obstetrics & Gynecology
Volume 177, Issue 4 , Pages 959-963 , October 1997

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