American Journal of Obstetrics & Gynecology
Volume 204, Issue 1 , Pages 56.e1-56.e6 , January 2011

Oxytocin exposure during labor among women with postpartum hemorrhage secondary to uterine atony

Presented as an abstract at the 57th Annual Scientific Meeting of the Society for Gynecologic Investigation, Orlando, FL, March 24-27, 2010.

  • Chad A. Grotegut, MD

      Affiliations

    • Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, NC
    • ,
  • Michael J. Paglia, MD, PhD

      Affiliations

    • Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Geisinger Medical Center, Danville, PA
    • ,
  • Lauren N.C. Johnson, MD

      Affiliations

    • Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, NC
    • ,
  • Betty Thames, RN, BS

      Affiliations

    • Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, NC
    • ,
  • Andra H. James, MD, MPH

      Affiliations

    • Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, NC

Received 3 May 2010 ,Revised 7 July 2010 ,Accepted 16 August 2010.

References 

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  2. Chang J, Elam-Evans LD, Berg CJ, et al. Pregnancy-related mortality surveillance–United States, 1991–1999. MMWR Surveill Summ. 2003;52:1–8
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  12. Balki M, Cristian AL, Kingdom J, Carvalho JC. Oxytocin pretreatment of pregnant rat myometrium reduces the efficacy of oxytocin but not of ergonovine maleate or prostaglandin F 2 alpha. Reprod Sci. 2010;17:269–277
  13. Amico JA, Seitchik J, Robinson AG. Studies of oxytocin in plasma of women during hypocontractile labor. J Clin Endocrinol Metab. 1984;58:274–279
  14. Seitchik J, Amico J, Robinson AG, Castillo M. Oxytocin augmentation of dysfunctional labor, IV: oxytocin pharmacokinetics. Am J Obstet Gynecol. 1984;150:225–228
  15. Daniel-Spiegel E, Weiner Z, Ben-Shlomo I, Shalev E. For how long should oxytocin be continued during induction of labor?. BJOG. 2004;111:331–334
  16. Clark S, Belfort M, Saade G, et al. Implementation of a conservative checklist-based protocol for oxytocin administration: maternal and newborn outcomes. Am J Obstet Gynecol. 2007;197:480.e1–480.e5
  17. Knight M, Callaghan WM, Berg C, et al. Trends in postpartum hemorrhage in high resource countries: a review and recommendations from the international postpartum hemorrhage collaborative group. BMC Pregnancy Childbirth. 2009;9:55

 Funding was provided by National Institutes of Health Grant no. K12-HD-043446 (C.A.G.).

 Reprints not available from the authors.

 Cite this article as: Grotegut CA, Paglia MJ, Johnson LNC, et al. Oxytocin exposure during labor among women with postpartum hemorrhage secondary to uterine atony. Am J Obstet Gynecol 2011;204:56.e1-6.

PII: S0002-9378(10)01026-4

doi: 10.1016/j.ajog.2010.08.023

American Journal of Obstetrics & Gynecology
Volume 204, Issue 1 , Pages 56.e1-56.e6 , January 2011

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