American Journal of Obstetrics & Gynecology
Volume 203, Issue 5 , Pages 481.e1-481.e9 , November 2010

Detection of cervical cancer and its precursors by endocervical curettage in 13,115 colposcopically guided biopsy examinations

  • Julia C. Gage, PhD, MPH

      Affiliations

    • Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD
    • Corresponding Author InformationReprints: Julia C. Gage, PhD, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd., Room 7013, MSC 7234, Rockville, MD 20892-7234
    • ,
  • Máire A. Duggan, MD

      Affiliations

    • Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, AB, Canada
    • ,
  • Jill G. Nation, MD

      Affiliations

    • Department of Obstetrics and Gynecology, University of Calgary, Calgary, AB, Canada
    • ,
  • Song Gao, MSc

      Affiliations

    • Alberta Cervical Cancer Screening Program, Alberta Cancer Board, Edmonton, AB, Canada
    • ,
  • Philip E. Castle, PhD, MPH

      Affiliations

    • Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD

Received 8 April 2010 ,Revised 5 May 2010 ,Accepted 17 June 2010.

References 

  1. Abu J, Davies Q. Endocervical curettage at the time of colposcopic assessment of the uterine cervix. Obstet Gynecol Surv. 2005;60:315–320
  2. Driggers RW, Zahn CM. To ECC or not to ECC: the question remains. Obstet Gynecol Clin North Am. 2008;35:583–597viii
  3. Ferenczy A. Endocervical curettage has no place in the routine management of women with cervical intraepithelial neoplasia: debate. Clin Obstet Gynecol. 1995;38:644–648
  4. Helmerhorst TJ. Clinical significance of endocervical curettage as part of colposcopic evaluation (A review). Int J Gynecol Cancer. 1992;2:256–262
  5. Moniak CW, Kutzner S, Adam E, Harden J, Kaufman RH. Endocervical curettage in evaluating abnormal cervical cytology. J Reprod Med. 2000;45:285–292
  6. Noller KL. Endocervical curettage: a technique in search of an indication? Debate. Clin Obstet Gynecol. 1995;38:649–652
  7. Agpar BS, Brotzman GL, Rubin MM. Principles and technique of colposcopic exam. In:  Agpar BS,  Brotzman GL,  Spitzer M editor. Colposcopy principles and practice: an integrated textbook and atlas. Philadelphia: Saunders; 2008;p. 115
  8. Solomon D, Stoler M, Jeronimo J, Khan M, Castle P, Schiffman M. Diagnostic utility of endocervical curettage in women undergoing colposcopy for equivocal or low-grade cytologic abnormalities. Obstet Gynecol. 2007;110(2 Pt 1):288–295
  9. Pretorius RG, Zhang WH, Belinson JL, et al. Colposcopically directed biopsy, random cervical biopsy, and endocervical curettage in the diagnosis of cervical intraepithelial neoplasia II or worse. Am J Obstet Gynecol. 2004;191:430–434
  10. Massad LS, Collins YC. Using history and colposcopy to select women for endocervical curettage (Results from 2,287 cases). J Reprod Med. 2003;48:1–6
  11. Irvin W, Flora S, Andersen W, Stoler M, Taylor P, Rice L. Endocervical curettage (Does it contribute to the management of patients with abnormal cervical cytology?). J Reprod Med. 2004;49:1–7
  12. Wright TC, Massad LS, Dunton CJ, Spitzer M, Wilkinson EJ, Solomon D. 2006 consensus guidelines for the management of women with abnormal cervical cancer screening tests. Am J Obstet Gynecol. 2007;197:346–355
  13. ACOG practice bulletin no. 99: management of abnormal cervical cytology and histology. Obstet Gynecol. 2008;112:1419–1444
  14. Williams DL, Dietrich C, McBroom J. Endocervical curettage when colposcopic examination is satisfactory and normal. Obstet Gynecol. 2000;95(6 Pt 1):801–803
  15. Srodon M, Parry Dilworth H, Ronnett BM. Atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion: diagnostic performance, human papillomavirus testing, and follow-up results. Cancer. 2006;108:32–38
  16. Barreth D, Schepansky A, Capstick V, Johnson G, Steed H, Faught W. Atypical squamous cells-cannot exclude high-grade squamous intraepithelial lesion (ASC-H): a result not to be ignored. J Obstet Gynaecol Can. 2006;28:1095–1098
  17. Sherman ME, Wang SS, Tarone R, Rich L, Schiffman M. Histopathologic extent of cervical intraepithelial neoplasia 3 lesions in the atypical squamous cells of undetermined significance low-grade squamous intraepithelial lesion triage study: implications for subject safety and lead-time bias. Cancer Epidemiol Biomarkers Prev. 2003;12:372–379
  18. Castle PE, Schiffman M, Wheeler CM, Solomon D. Evidence for frequent regression of cervical intraepithelial neoplasia-grade 2. Obstet Gynecol. 2009;113:18–25
  19. Castle PE, Fetterman B, Poitras N, Lorey T, Shaber R, Kinney W. Relationship of atypical glandular cell cytology, age, and human papillomavirus detection to cervical and endometrial cancer risks. Obstet Gynecol. 2010;115(2 Pt 1):243–248
  20. Pretorius RG, Kim RJ, Belinson JL, Elson P, Qiao YL. Inflation of sensitivity of cervical cancer screening tests secondary to correlated error in colposcopy. J Low Genit Tract Dis. 2006;10:5–9
  21. Gage JC, Hanson VW, Abbey K, et al. Number of cervical biopsies and sensitivity of colposcopy. Obstet Gynecol. 2006;108:264–272
  22. McCredie MR, Sharples KJ, Paul C, et al. Natural history of cervical neoplasia and risk of invasive cancer in women with cervical intraepithelial neoplasia 3: a retrospective cohort study. Lancet Oncol. 2008;9:425–434

 J.C.G. and P.E.C. were supported by the Intramural Research Program of the National Cancer Institute, National Institutes of Health.

 Cite this article as: Gage JC, Duggan MA, Nation JG, et al. Detection of cervical cancer and its precursors by endocervical curettage in 13,115 colposcopically guided biopsy examinations. Am J Obstet Gynecol 2010;203:481.e1-9.

PII: S0002-9378(10)00823-9

doi: 10.1016/j.ajog.2010.06.048

American Journal of Obstetrics & Gynecology
Volume 203, Issue 5 , Pages 481.e1-481.e9 , November 2010

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