American Journal of Obstetrics & Gynecology
Volume 203, Issue 4 , Pages 366.e1-366.e6 , October 2010

Plasma 25-hydroxyvitamin D levels in early-onset severe preeclampsia

Presented at the 30th Annual Meeting of the Society for Maternal-Fetal Medicine, Chicago, IL, Feb. 1-6, 2010.

  • Christopher J. Robinson, MD, MSCR

      Affiliations

    • Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston, SC
  • ,
  • Mark C. Alanis, MD, MSCR

      Affiliations

    • Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston, SC
  • ,
  • Carol L. Wagner, MD

      Affiliations

    • Department of Pediatrics, Medical University of South Carolina, Charleston, SC
  • ,
  • Bruce W. Hollis, PhD

      Affiliations

    • Department of Pediatrics, Medical University of South Carolina, Charleston, SC
  • ,
  • Donna D. Johnson, MD

      Affiliations

    • Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston, SC

Received 1 March 2010 ,Revised 8 June 2010 ,Accepted 17 June 2010.

  • Image Result

    Maternal plasma 25-hydroxyvitamin D in early-onset severe preeclampsia (EOSPE) vs control subjects

    Patients with early-onset severe preeclampsia had significantly decreased levels of 25-hydroxyvitamin

    Maternal plasma 25-hydroxyvitamin D in early-onset severe preeclampsia (EOSPE) vs control subjects

    Patients with early-onset severe preeclampsia had significantly decreased levels of 25-hydroxyvitamin D relative to healthy control pregnancies that were matched for gestational age at plasma sampling (median 25-hydroxyvitamin D, 18 vs 32 ng/mL; P < .001). The probability value was determined by Mann Whitney U test.

    Robinson. Plasma 25-OH-vitamin D levels in early-onset severe preeclampsia. Am J Obstet Gynecol 2010.

  • Image Result
    Plasma 25-OH-D by race and early-onset severe preeclampsia (EOSPE) statusAfrican American and white women with early-onset severe preeclampsia were noted to have decreased plasma levels of 25-hydroxyv

    Plasma 25-OH-D by race and early-onset severe preeclampsia (EOSPE) status

    African American and white women with early-onset severe preeclampsia were noted to have decreased plasma levels of 25-hydroxyvitamin D (25-OH-D) relative to matched-race, control pregnancies. African American women were noted to have the lowest plasma 25-OH-D levels when compared with white women. The bars represent mean 25-OH-D levels (mean ± SEM). The probability values were determined with the Tukey-Kramer test.

    Robinson. Plasma 25-OH-vitamin D levels in early-onset severe preeclampsia. Am J Obstet Gynecol 2010.

 Reprints not available from the authors.

 Supported by a Clinical and Translational Science K12 Award, Medical University of South Carolina.

 Cite this article as: Robinson CJ, Alanis MC, Wagner CL, et al. Plasma 25-hydroxyvitamin D levels in early-onset severe preeclampsia. Am J Obstet Gynecol 2010;203:366.e1-6.

PII: S0002-9378(10)00811-2

doi: 10.1016/j.ajog.2010.06.036

American Journal of Obstetrics & Gynecology
Volume 203, Issue 4 , Pages 366.e1-366.e6 , October 2010