American Journal of Obstetrics & Gynecology
Volume 203, Issue 2 , Pages 124.e1-124.e7, August 2010

Decreased term and postterm birthweight in the United States: impact of labor induction

Presented at the 21st Annual Meeting of the Society for Pediatric and Perinatal Epidemiologic Research, Chicago, IL, June 23-24, 2008.

  • Xun Zhang, PhD

      Affiliations

    • Department of Pediatrics, McGill University Faculty of Medicine, Montreal, Quebec
  • ,
  • K.S. Joseph, MD, PhD

      Affiliations

    • Department of Obstetrics and Gynecology and the School of Population and Public Health, University of British Columbia and British Columbia's Women's Hospital and Health Center, Vancouver, British Columbia, Canada
  • ,
  • Michael S. Kramer, MD

      Affiliations

    • Department of Pediatrics, McGill University Faculty of Medicine, Montreal, Quebec
    • Department of Epidemiology, Biostatistics, and Occupational Health, McGill University Faculty of Medicine, Montreal, Quebec

published online 17 May 2010.

Objective

We sought to assess recent trends in falling mean birthweight (BW) and gestational age (GA) among US non-Hispanic white singleton live births ≥37 weeks of gestation and the contribution of increased rates of induction to these trends.

Study Design

This was an ecological study based on US vital statistics from 1992 through 2003.

Results

From 1992 through 2003, mean BW fell by 37 g, mean GA by 3 days, and macrosomia rates by 25%. Rates of induction nearly doubled from 14% to 27%. Our ecological state-level analysis showed that the increased rate of induction was significantly associated with reduced mean BW (r = –0.54; 95% confidence interval [CI], –0.71 to –0.29), mean GA (r = –0.44; 95% CI, –0.65 to –0.17), and rate of macrosomia (r = –0.55; 95% CI, –0.74 to –0.32).

Conclusion

Increasing use of induction is a likely cause of the observed recent declines in BW and GA. The impact of these trends on infant and long-term health warrants attention and investigation.

Key words: birthweight, cesarean section, ecological analysis, gestational age, labor induction, vital statistics

 

 Supported in part by a grant from the Canadian Institutes of Health Research.

 Reprints not available from the authors.

 Cite this article as: Zhang X, Joseph KS, Kramer MS. Decreased term and postterm birthweight in the United States: impact of labor induction. Am J Obstet Gynecol 2010;203:124.e1-7.

PII: S0002-9378(10)00363-7

doi:10.1016/j.ajog.2010.03.044

American Journal of Obstetrics & Gynecology
Volume 203, Issue 2 , Pages 124.e1-124.e7, August 2010