American Journal of Obstetrics & Gynecology
Volume 203, Issue 3 , Pages 209.e1-209.e6, September 2010

Reproductive outcomes in subsequent pregnancies after a pregnancy complicated by open maternal-fetal surgery (1996–2007)

Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, Philadelphia, PA

Received 23 November 2009; received in revised form 20 January 2010; accepted 18 March 2010. published online 31 May 2010.

Objective

The reproductive and gynecologic outcomes for women after the pregnancy complicated by open maternal-fetal surgery (OMFS) were evaluated.

Study Design

The retrospective review identified 93 women with OMFS from a single institution (1996–2007). Consent and questionnaires were sent to women. Institutional review board approval was obtained from the Committee for Protection of Human Subjects.

Results

The total return rate was 57.3%. Total pregnancies reported were 47, with 36 delivering after 20 weeks' gestation. The uterine dehiscence and rupture rates were 14% and 14%, respectively. Fetal anomalies occurred in 4 subsequent pregnancies. Normal conception occurred in 98% of subsequent pregnancies. Gynecologic issues were reported by 8 women, with infertility, abdominal pain, and ovarian and uterine factors.

Conclusion

The reproductive outcomes of uterine dehiscence (14%) and rupture (14%) in a subsequent pregnancy continue to be a major counseling issue for OMFS. Fertility and gynecologic factors do not appear to be increased for women undergoing OMFS.

Key words: fetal anomalies, in utero therapy, maternal-fetal surgery, maternal-fetal surgery risk, open maternal-fetal surgery outcomes, uterine dehiscence, uterine rupture

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 Reprints not available from the authors.

 Cite this article as: Wilson RD, Lemerand K, Johnson MP, et al. Reproductive outcomes in subsequent pregnancies after a pregnancy complicated by open maternal-fetal surgery (1996–2007). Am J Obstet Gynecol 2010;203:209.e1-6.

PII: S0002-9378(10)00348-0

doi:10.1016/j.ajog.2010.03.029

American Journal of Obstetrics & Gynecology
Volume 203, Issue 3 , Pages 209.e1-209.e6, September 2010

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