Preschool neurodevelopmental outcome of children following fetal myelomeningocele closure

WPPSI-III preschool neurocognitive outcomes

Plot of test scores for Wechsler Preschool and Primary Scale of Intelligence, Third Edition, verbal intelligence quotient (IQ), performance IQ, full IQ, and processing speed for fetal myelomeningocele (fMMC) children undergoing standardized cognitive testing. Percentage of patients is shown on y-axis, and tests scores are displayed on x-axis. Expected population mean score is 100 with SD of 15.

WPPSI-III, Wechsler Preschool and Primary Scale of Intelligence, Third Edition.

Danzer. Neurodevelopmental outcome of children following fMMC closure. Am J Obstet Gynecol 2010.

Infant to preschool comparative trends

Evaluation of individual neurodevelopmental scores (black lines) of fetal myelomeningocele children who returned serially until 5 years of age. Dotted lines represent expected average score ranges for population norms (100 ± 15).

MDI, Mental Developmental Index; VIQ, verbal intelligence quotient; WPPSI-III, Wechsler Preschool and Primary Scale of Intelligence, Third Edition.

Danzer. Neurodevelopmental outcome of children following fMMC closure. Am J Obstet Gynecol 2010.