American Journal of Obstetrics & Gynecology
Volume 202, Issue 5 , Pages 485.e1-485.e9 , May 2010

Effect of hormone replacement and selective estrogen receptor modulators (SERMs) on the biomechanics and biochemistry of pelvic support ligaments in the cynomolgus monkey (Macaca fascicularis)

Presented in part at the 34th Annual Scientific Meeting of the Society of Gynecologic Surgeons, Savannah, GA, April 12-17, 2008, and in full at the 30th Annual Scientific Meeting of the American Urogynecologic Society, Hollywood, FL, Sept. 24-26, 2009.

  • Azin Shahryarinejad, MD, MPH

      Affiliations

    • Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Keck School of Medicine at USC, Los Angeles, CA
    • ,
  • Thomas R. Gardner, MCE

      Affiliations

    • Center for Orthopaedic Research, Department of Orthopaedic Surgery, Columbia University College of Physicians and Surgeons, New York, NY
    • ,
  • J. Mark Cline, DVM, PhD

      Affiliations

    • Section on Comparative Medicine, Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC
    • ,
  • William N. Levine, MD

      Affiliations

    • Center for Orthopaedic Research, Department of Orthopaedic Surgery, Columbia University College of Physicians and Surgeons, New York, NY
    • ,
  • Haley A. Bunting, MS

      Affiliations

    • Center for Orthopaedic Research, Department of Orthopaedic Surgery, Columbia University College of Physicians and Surgeons, New York, NY
    • ,
  • Michael D. Brodman, MD

      Affiliations

    • Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Mount Sinai School of Medicine, New York, NY
    • ,
  • Charles J. Ascher-Walsh, MD

      Affiliations

    • Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Mount Sinai School of Medicine, New York, NY
    • ,
  • Richard J. Scotti, MD

      Affiliations

    • Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Keck School of Medicine at USC, Los Angeles, CA
    • ,
  • Michael D. Vardy, MD

      Affiliations

    • Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Mount Sinai School of Medicine, New York, NY

Received 4 August 2009 ,Revised 10 November 2009 ,Accepted 24 January 2010.

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 Cite this article as: Shahryarinejad A, Gardner TR, Cline JM, et al. Effect of hormone replacement and selective estrogen receptor modulators (SERMs) on the biomechanics and biochemistry of pelvic support ligaments in the cynomolgus monkey (Macaca fascicularis). Am J Obstet Gynecol 2010;202:485.e1-9.

 Reprints not available from the authors.

 This study was funded by the American College of Obstetricians and Gynecologists ACOG/Solvay Research Award in Menopause. The parent study was supported in part by Johnson and Johnson Pharmaceutical Research and Development, LLC.

PII: S0002-9378(10)00104-3

doi: 10.1016/j.ajog.2010.01.074

American Journal of Obstetrics & Gynecology
Volume 202, Issue 5 , Pages 485.e1-485.e9 , May 2010

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