American Journal of Obstetrics & Gynecology
Volume 203, Issue 2 , Pages 105.e1-105.e13 , August 2010

Uterine artery embolization vs hysterectomy in the treatment of symptomatic uterine fibroids: 5-year outcome from the randomized EMMY trial

  • Sanne M. van der Kooij, MD

      Affiliations

    • Department of Radiology, Academic Medical Center, Amsterdam, The Netherlands
    • Department of Gynecology, Academic Medical Center, Amsterdam, The Netherlands
    • Corresponding Author InformationReprints: Sanne M. van der Kooij, MD, Academic Medical Center, Department of Gynecology, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    • ,
  • Wouter J.K. Hehenkamp, MD, PhD

      Affiliations

    • Department of Gynecology, Academic Medical Center, Amsterdam, The Netherlands
    • ,
  • Nicole A. Volkers, MD, PhD

      Affiliations

    • Department of Radiology, Academic Medical Center, Amsterdam, The Netherlands
    • ,
  • Erwin Birnie, PhD

      Affiliations

    • Institute of Health Policy and Management, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Willem M. Ankum, MD, PhD

      Affiliations

    • Department of Gynecology, Academic Medical Center, Amsterdam, The Netherlands
    • ,
  • Jim A. Reekers, MD, PhD

      Affiliations

    • Department of Radiology, Academic Medical Center, Amsterdam, The Netherlands

Received 8 July 2009 ,Revised 22 October 2009 ,Accepted 19 January 2010.

  • Image Result

    Trial profile

    Profile represents the flow of patients through the trial.

    MRI, magnetic resonance imaging; UAE, uterine artery embolization.

    van der Kooij. UAE vs hysterectomy for uterine fibroids. Am J O

    Trial profile

    Profile represents the flow of patients through the trial.

    MRI, magnetic resonance imaging; UAE, uterine artery embolization.

    van der Kooij. UAE vs hysterectomy for uterine fibroids. Am J Obstet Gynecol 2010.

  • Image Result
    Kaplan-Meier curve for preservation of the uterus after UAECurve represents preservation of the uterus after UAE. Censored means that a patient was lost to follow up and had not undergone a hysterecto

    Kaplan-Meier curve for preservation of the uterus after UAE

    Curve represents preservation of the uterus after UAE. Censored means that a patient was lost to follow up and had not undergone a hysterectomy before the last follow-up moment.

    UAE, uterine artery embolization.

    van der Kooij. UAE vs hysterectomy for uterine fibroids. Am J Obstet Gynecol 2010.

  • Image Result
    Wiklund scoreThe graph represents the Wiklund score for menopausal symptoms until 5 years of follow up. Scores range from 0–51; the higher scores represent more serious menopausal symptoms.UAE, uterin

    Wiklund score

    The graph represents the Wiklund score for menopausal symptoms until 5 years of follow up. Scores range from 0–51; the higher scores represent more serious menopausal symptoms.

    UAE, uterine artery embolization.

    van der Kooij. UAE vs hysterectomy for uterine fibroids. Am J Obstet Gynecol 2010.

  • Image Result
    Graphs show scores until 5 years of follow-up evaluationA, Short Form 36 (SF-36): Mental Component Summary: scores range from 0–100 (higher scores mean a better mental quality of life); B, Short Form

    Graphs show scores until 5 years of follow-up evaluation

    A, Short Form 36 (SF-36): Mental Component Summary: scores range from 0–100 (higher scores mean a better mental quality of life); B, Short Form 36 (SF-36): Physical Component Summary; scores range from 0–100 (higher scores mean a better physical quality of life); C, Urogenital Distress Inventory (UDI): scores range from 0–100 (higher scores indicate worse functioning); D, Defecation Distress Inventory (DDI): scores range from 0–100 (higher scores indicate worse functioning).

    UAE, uterine artery embolization.

    van der Kooij. UAE vs hysterectomy for uterine fibroids. Am J Obstet Gynecol 2010.

 The EMMY trial participants and hospitals are listed with the full-length article at www.AJOG.org.

 Supported by ZonMw “Netherlands Organization for Health Research and Development” (Grant application no: 945-01-017) and by Boston Scientific Corporation, The Netherlands.

 Cite this article as: van der Kooij SM, Hehenkamp WJK, Volkers NA, et al. Uterine artery embolization vs hysterectomy in the treatment of symptomatic uterine fibroids: 5-year outcome from the randomized EMMY trial. Am J Obstet Gynecol 2010;203:105.e1-13.

PII: S0002-9378(10)00079-7

doi: 10.1016/j.ajog.2010.01.049

American Journal of Obstetrics & Gynecology
Volume 203, Issue 2 , Pages 105.e1-105.e13 , August 2010

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