American Journal of Obstetrics & Gynecology
Volume 202, Issue 6 , Pages 559.e1-559.e4, June 2010

The prognostic role of uterine artery Doppler investigation in patients with severe early-onset preeclampsia

Department of Maternal-Fetal Medicine, ICGON, Fetal and Perinatal Medicine Research Group (IDIBAPS), and Center of Biomedical Research on Rare Diseases (CIBER-ER), Hospital Clinic-University of Barcelona, Spain

Received 26 June 2009; received in revised form 8 October 2009; accepted 19 January 2010. published online 29 March 2010.

Objective

The purpose of this study was to evaluate the prediction capacity of uterine artery Doppler investigation for maternal and neonatal complications in women who are admitted with severe early-onset preeclampsia.

Study Design

A uterine artery Doppler examination was performed at admission for patients with severe early-onset (<34 weeks of gestation) preeclampsia. The maternal and neonatal outcome of women with abnormal uterine Doppler results was compared with those with normal Doppler results.

Results

One hundred twenty patients were included. In 53% of them, uterine Doppler results were abnormal. This group had a lower gestational age at delivery (30.2 vs 32.7 weeks; P < .001) and a higher proportion of small-for-gestational age infants (87.5% vs 67.9%; P = .009). Neonatal (40.6% vs 14.3%; P = .01) and maternal (28.1% vs 5.4%; P = .001) complications were more common in the abnormal uterine Doppler group.

Conclusion

Women with severe early-onset preeclampsia are at higher risk of maternal and neonatal complications if abnormal uterine blood flow is present.

Key words: early-onset preeclampsia, uterine artery Doppler investigation

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 Authorship and contribution to the article is limited to the 6 authors indicated. There was no outside funding or technical assistance with the production of this article.

 Cite this article as: Meler E, Figueras F, Bennasar M, et al. The prognostic role of uterine artery Doppler investigation in patients with severe early-onset preeclampsia. Am J Obstet Gynecol 2010;202:559.e1-4.

PII: S0002-9378(10)00078-5

doi:10.1016/j.ajog.2010.01.048

American Journal of Obstetrics & Gynecology
Volume 202, Issue 6 , Pages 559.e1-559.e4, June 2010